Regulatory mechanisms of meiosis
Regulatory mechanisms of meiosis
批准号:
16002010
负责人:
YAMAMOTO Masayuki
金额:
$227.05万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Specially Promoted Research
财政年份:
2004
资助国家:
日本
项目状态:
已结题
起止时间:
2004 至 2008
中文摘要
分裂酵母を材料に減数分裂を制御する分子機構を解析し、減数分裂のための遺伝子のmRNAにはそれらを栄養増殖時には細胞から選択的に取り除くための目印が埋め込まれていることを発見し、またそれらが減数分裂時には減数分裂マスター制御因子Mei2pによって安定化されるメカニズムを解明した。
英文摘要
分裂酵母を材料に減数分裂を制御する分子機構を解析し、減数分裂のための遺伝子のmRNAにはそれらを栄養増殖時には細胞から選択的に取り除くための目印が埋め込まれていることを発見し、またそれらが減数分裂時には減数分裂マスター制御因子Mei2pによって安定化されるメカニズムを解明した。
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DOI:
10.1073/pnas.0608510104
发表时间:
2007-02-27
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子:
11.1
作者:
[Urano, Jun, Sato, Tatsuhiro, Tamanoi, Fuyuhiko]
通讯作者:
Tamanoi, Fuyuhiko
DOI:
10.1038/nature03406
发表时间:
2005-03-24
期刊:
NATURE
影响因子:
64.8
作者:
[Izawa, D, Goto, M, Yamamoto, M]
通讯作者:
Yamamoto, M
Fission yeast Meslp ensures the onset of meiosis II by blocking degradation of cyclin Cdc13p.
裂殖酵母 Meslp 通过阻止细胞周期蛋白 Cdc13p 的降解来确保减数分裂 II 的开始。
DOI:
--
发表时间:
2005
期刊:
Nature 434
影响因子:
--
作者:
[Izawa, D., Goto, M., Yamashita, A., Yamano, H., and Yamamoto, M.]
通讯作者:
M.
Selective elimination of mRNA as a novel paradigm for the regulation of meiosis.
选择性消除 mRNA 作为减数分裂调节的新范例。
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[Yamamoto, M.]
通讯作者:
M.
DOI:
10.1016/j.devcel.2007.12.010
发表时间:
2008-03-01
期刊:
DEVELOPMENTAL CELL
影响因子:
11.8
作者:
[Kimata, Yuu, Trickey, Michelle, Yamano, Hiroyuki]
通讯作者:
Yamano, Hiroyuki
共 33 条
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Mechanism of Nrf2-mediated self-renewal of hematopoietic stem cells
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Studies on transcriptional regulation of genes involving synthesis of lignans and tocopherols in sesame.
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Regulatory Mechanisms of Meiosis in Fission Yeast
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Formative Process of Modern Typography in the 20th Century England
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Molecular Mechanisms of Adaptive Responses to Food and Oxygen
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Interactions between cloud microphysical processes and vertical air motions in the tropical and midlatitude regions
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Development of Autonomous Mobile Guide System for Persons with Visual Impairment
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Molecular mechanisms for hemato-vascular formation
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Analysis of biological function of regulatory network composed of bZip transcription factors
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Development of monitoring system of toxic chemicals base on the Nrf2-dependent detoxification pathway
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APPLICATION OF GENE MANIPULATION TECHNOLOGY TO GENERATION OF MODEL ANIMALS FOR ENVIRONMENTAL ASSESSMENT
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Molecular Mechanisms for the Regulation of Meiosis
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