In vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolates
In vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolates
批准号:
21790425
负责人:
TATSUNO Ichiro
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012
中文摘要
点击翻译按钮获取中文摘要
英文摘要
I have studied about in vivo suppression of the toxicity in the invasive M-1 group A Streptococcal isolates, using mouse infection model. As results(1) I could partially suppressed the toxicity in an invasive M-1 group A Streptococcal isolate, suppressing the NADase activity of Nga protein which is secreted toxin;(2) I have presented the supportive evidence that Nga (also known as SPN) has a NADase-independent function;(3) I provided other potential targets to suppress the Streptococcal virulence.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
Characterization of virulence-associated and cell-wall-located DNase of Streptococcus pyogenes
化脓性链球菌毒力相关和细胞壁定位 DNase 的表征
DOI:
--
发表时间:
2010
期刊:
Microbiology 156
影响因子:
--
作者:
[長谷川忠男, 立野一郎(4番目)]
通讯作者:
立野一郎(4番目)
A群レンサ球菌における二成分制御系センサータンパク質の機能解析
A 族链球菌双组分调节系统传感器蛋白的功能分析
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[長谷川忠男, 立野一郎(4番目), 立野一郎]
通讯作者:
立野一郎
Characterization of Streptococcus pyogenes isolated from balanoposthitis patients presumably transmitted by penile-oral sexual intercourse
从可能通过阴茎口性交传播的龟头包皮炎患者中分离出的化脓性链球菌的特征
DOI:
10.1007/s00284-010-9581-x
发表时间:
2010
期刊:
Curr Microbiol
影响因子:
2.6
作者:
[Minami M, Wakimoto Y, Matsumoto M, Matsui H, Kubota Y, Okada A, Isaka M, Tatsuno I, Tanaka Y, Hasegawa T]
通讯作者:
Hasegawa T
Analysis of two-component sensor proteins involved in response to acid stimuli in Streptococcus pyogenes.
分析化脓性链球菌中参与酸刺激反应的双组分传感器蛋白。
DOI:
10.1099/mic.0.050534-0
发表时间:
2011
期刊:
Microbiology
影响因子:
1.5
作者:
[Ichikawa M, Minami M, Isaka M, Tatsuno I, Hasegawa T]
通讯作者:
Hasegawa T
DOI:
10.1111/j.1600-0463.2009.02574.x
发表时间:
2010-03-01
期刊:
APMIS
影响因子:
2.8
作者:
[Hasegawa, Tadao, Okamoto, Akira, Ohta, Michio]
通讯作者:
Ohta, Michio
共 8 条
Elucidation of Bone Epigenetics with NFATc1 Complex Analysis using Cross-linking Method.
-
批准号:24390239
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.48万
-
财政年份:2012
-
负责人:TATSUNO Ichiro
-
依托单位:
The role of tumor suppressor candidate 5 (BEC1/TUSC5) in adipocyte differentiation
-
批准号:21591169
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2009
-
负责人:TATSUNO Ichiro
-
依托单位:
Characterization of the NAD-glycohydrolase in streptococcal strains
-
批准号:19590452
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:TATSUNO Ichiro
-
依托单位:
The functions of two novel genes isolated from brain endothelial cells.
-
批准号:17590916
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:2005
-
负责人:TATSUNO Ichiro
-
依托单位:
Cerebral endothelial cell and Neurotrophins
-
批准号:13671177
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.73万
-
财政年份:2001
-
负责人:TATSUNO Ichiro
-
依托单位:
Analysis of novel adherence factors for initial infection in Enterohemorrhagic Escherichia coli O157Sakai
-
批准号:13670263
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2001
-
负责人:TATSUNO Ichiro
-
依托单位:
海外基金