Sweet Taste Receptor Expressed in Pancreatic・-Cells is Involved in Novel Insulin Secretion Pathway

我们用夏普测量系统分析了β细胞中的信号传递机制。结果，我们观察到Ca^2+、cAMP、二酰甘油（DAG）和蛋白激酶C（PKC）在葡萄糖刺激下立即产生激活。该响应澄清了与传统上认为的葡萄糖代谢无关对象中的代谢依赖性响应不同的新机制的存在。

We analyzed the signal transmission mechanism in the β cell using the sharp system of measurement. As a result, we observed activation of Ca^<2+>, cAMP, diacylglycerol (DAG) and protein kinase C (PKC) being generated instantly in response to glucose stimulation . The response clarified that the new mechanism that was different from the metabolism-dependent reply that had been thought about conventionally in a glucose metabolism-independent object existed.