Feasibility of using bio adhesives to repair retinal detachment and ischemic retinal diseases.

虽然手术策略的孔源性视网膜脱离治疗发展，仍有改进的余地。在本项目中，我们研究了明胶-微生物转谷氨酰胺酶（明胶- mtg）复合物治疗实验性视网膜脱离的效果。玻璃体切除术后，明胶- mtg复合物覆盖视网膜裂孔超过7天，炎症不明显。所有治疗过的眼睛视网膜都重新附着。此外，我们还研究了眼粘手术装置（OVD）对实验性视网膜脱离的暂时性填塞效果。视网膜表面的OVD消失，视网膜重新附着。此外，刚性内窥镜放置在角膜表面观察周围视网膜的有效性进行了评估。该技术操作简单，可用于观察周围视网膜，特别是无晶状眼和假晶状眼。

Although surgical strategies for rhegmatogenous retinal detachment treatments developed, there is still room for improvement. In this project, we investigated the effect of using gelatin-microbial transglutaminase (gelatin-mTG) complex for treating experimental retinal detachment. Gelatin-mTG complex covered the retinal tear for more than 7 days after the vitrectomy with less prominent inflammation. Reattachment of the retina occurred in all treated eyes. In addition, we investigated the temporary tamponade effects of an ophthalmic viscosurgical device (OVD) for experimental retinal detachment. The OVD on the retinal surface had disappeared and the retina was reattached. Furthermore, the usefulness of rigid endoscopy placed on the corneal surface to observe the peripheral retina was evaluated. This technique was simple to manipulate and useful for observing the peripheral retina, in particular, in aphakic and pseudo-phakic eyes.