课题基金 / 基金详情

Myocardial protection by induced stress protein: the multilateral strategy for cardioprotection

Myocardial protection by induced stress protein: the multilateral strategy for cardioprotection
诱导应激蛋白的心肌保护:心脏保护的多边策略
批准号:
23592994
负责人:
KITAHATA Hiroshi
金额:
$3.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2013

项目摘要

项目成果

KITAHATA Hiroshi的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
An anti-ulcer drug, geranylgeranylacetone (GGA), can protect the heart against ischemia/reperfusion injury by inducing heat shock protein. The purpose of this study was to determine whether integral membrane proteins, caveolins (Cav) are essential for GGA-induced myocardial protection and to evaluate the interaction between cardioprotection by GGA and anesthetic pre-/postconditioning.The results of experiments with wild-type and Cav-3 knockout mice have proved that GGA-iduced cardioprotection is dependent on Cav-3 expression. There was no interaction between the myocardial protection with GGA and opioid pre- and postconditioning in our experimental setting using cultured neonatal rat ventricular myocytes.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI: --
发表时间: 2011
期刊: Anesth Analg
影响因子: 5.7
作者: [Kawahito S, Kawano T, Kitahata H, Oto J, Takahashi A, Takaishi K, Harada N, Nakagawa T, Kinoshita H, Azma T, Nakaya Y, Oshita S]
通讯作者: Oshita S
Anesthetic Cardioprotection in Relation to Mitochondria: Basic Science.
与线粒体相关的麻醉心脏保护:基础科学。
DOI: 10.2174/1381612820666140204110101
发表时间: 2014
期刊: Current Pharmaceutical Design
影响因子: 3.1
作者: [Mio Y, Uezono S, Kitahata H]
通讯作者: Kitahata H
Geranylgeranylacetone induced delayed cardiac preconditioning requires caveolin-3.
香叶基香叶基丙酮诱导的延迟心脏预处理需要 Caveolin-3。
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Tsutsumi YM]
通讯作者: Tsutsumi YM
Protective effects of amino acids on the ischemic myocardium via mTOR/S6 kinase pathway.
氨基酸通过 mTOR/S6 激酶途径对缺血心肌的保护作用。
DOI: --
发表时间: 2012
期刊:
影响因子: --
作者: [Tsutsumi YM, et al.]
通讯作者: et al.
13
    Myocardial protection via mTOR - Proposal of novel therapy for ischemia-reperfusion injury
    • 批准号:
      17K11909
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2017
    • 负责人:
      KITAHATA Hiroshi
    • 依托单位:
    Role of sirtuin in volatile anesthetic-induced cardiac protection.
    • 批准号:
      26463071
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2014
    • 负责人:
      KITAHATA Hiroshi
    • 依托单位:
    The establishment of strategy for perioperative myocardial protection by intraoperative ultra-short-acting β1 bloctker
    • 批准号:
      18591707
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.52万
    • 财政年份:
      2006
    • 负责人:
      KITAHATA Hiroshi
    • 依托单位:
    The influence of anesthetics on cardioprotection by stress-induced protein
    • 批准号:
      13671587
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.3万
    • 财政年份:
      2001
    • 负责人:
      KITAHATA Hiroshi
    • 依托单位:
    海外基金