Induction of multipotent germline stem cells from germline stem cells by epigenetic change.
Induction of multipotent germline stem cells from germline stem cells by epigenetic change.
批准号:
23790332
负责人:
TANAKA Takashi
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
To el uci date the mechani sm whi ch represses pl uri potency i n germline stem cells (GSCs), this study investigated whether epigenetic changes induce GS-mGS conversion. As a result, lentiviral transduction of shrnas for epigenetic modifiers did not induce GS-mGS conversion. These results suggest that pluripotency in GS cells is repressed by several pathways.
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DOI:
10.1095/biolreprod.111.095307
发表时间:
2012-05-01
期刊:
BIOLOGY OF REPRODUCTION
影响因子:
3.6
作者:
[Morimoto, Hiroko, Lee, Jiyoung, Shinohara, Takashi]
通讯作者:
Shinohara, Takashi
インテグリンシグナルによる精子幹細胞制御
整合素信号控制精子干细胞
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[]
通讯作者:
DOI:
10.1073/pnas.1015447108
发表时间:
2011-06-28
期刊:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子:
11.1
作者:
[Tanaka, Takashi, Hosokawa, Mihoko, Chuma, Shinichiro]
通讯作者:
Chuma, Shinichiro
DOI:
10.1016/j.stem.2011.08.011
发表时间:
2011-11-04
期刊:
CELL STEM CELL
影响因子:
23.9
作者:
[Takashima, Seiji, Kanatsu-Shinohara, Mito, Shinohara, Takashi]
通讯作者:
Shinohara, Takashi
DOI:
10.1095/biolreprod.111.090837
发表时间:
2011-07-01
期刊:
BIOLOGY OF REPRODUCTION
影响因子:
3.6
作者:
[Kanatsu-Shinohara, Mito, Kato-Itoh, Megumi, Shinohara, Takashi]
通讯作者:
Shinohara, Takashi
共 6 条
Study on quinone dimer formation and redox disproportionation in plant polyphenol metabolism
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批准号:20K07102
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.5万
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财政年份:2020
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负责人:TANAKA Takashi
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依托单位:
An approach to neural circuit reconstruction after brain injury targeting inflammation in the brain in elderly mice
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批准号:17K13079
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.58万
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财政年份:2017
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负责人:TANAKA Takashi
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依托单位:
Chemical study on non-enzymatic oxidation-reduction dismutation of plant polyphenol and verification of the generality
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批准号:17K08338
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2017
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负责人:TANAKA Takashi
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Integrated research of neural network reorganization following brain injury for clinical application
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批准号:15K16377
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.41万
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财政年份:2015
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负责人:TANAKA Takashi
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依托单位:
Ellagitannin biosynthesis via non-enzymatic quinone dimerization and redox dismutation
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批准号:26460125
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2014
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负责人:TANAKA Takashi
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依托单位:
The function of Myc family genes in self-renewal of spermatogonial stem cells
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批准号:25860210
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.66万
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财政年份:2013
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负责人:TANAKA Takashi
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依托单位:
Development of a new method for nondestructive evaluation of solid wood moisture content based on dual-energy X-ray absorptiometry
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批准号:24780170
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$3.0万
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财政年份:2012
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负责人:TANAKA Takashi
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依托单位:
Evaluation for Safety Assessment on Walkway at Shipyard by Fluctuation Analysis
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批准号:23760785
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.91万
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财政年份:2011
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负责人:TANAKA Takashi
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依托单位:
Clarification of molecular mechanisms how PDLIM2, a nuclear ubiquitin E3 ligase, regulates inflammatory responses
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批准号:20590499
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2008
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负责人:TANAKA Takashi
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依托单位:
Clarification of LIM protein family-mediated system that regulates innate immune responses.
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批准号:18590480
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.57万
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财政年份:2006
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负责人:TANAKA Takashi
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依托单位:
Study of substorm simulation
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批准号:15540429
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.18万
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财政年份:2003
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负责人:TANAKA Takashi
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依托单位:
Approach to Black Tea Pigments based on Bioorganic Chemistry of Catechin Oxidation
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批准号:12680594
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
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财政年份:2000
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负责人:TANAKA Takashi
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依托单位:
海外基金