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Induction of multipotent germline stem cells from germline stem cells by epigenetic change.

Induction of multipotent germline stem cells from germline stem cells by epigenetic change.
通过表观遗传改变从生殖干细胞诱导多能生殖干细胞。
批准号:
23790332
负责人:
TANAKA Takashi
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
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英文摘要
To el uci date the mechani sm whi ch represses pl uri potency i n germline stem cells (GSCs), this study investigated whether epigenetic changes induce GS-mGS conversion. As a result, lentiviral transduction of shrnas for epigenetic modifiers did not induce GS-mGS conversion. These results suggest that pluripotency in GS cells is repressed by several pathways.
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DOI: 10.1095/biolreprod.111.095307
发表时间: 2012-05-01
期刊: BIOLOGY OF REPRODUCTION
影响因子: 3.6
作者: [Morimoto, Hiroko, Lee, Jiyoung, Shinohara, Takashi]
通讯作者: Shinohara, Takashi
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: []
通讯作者:
DOI: 10.1073/pnas.1015447108
发表时间: 2011-06-28
期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
影响因子: 11.1
作者: [Tanaka, Takashi, Hosokawa, Mihoko, Chuma, Shinichiro]
通讯作者: Chuma, Shinichiro
DOI: 10.1016/j.stem.2011.08.011
发表时间: 2011-11-04
期刊: CELL STEM CELL
影响因子: 23.9
作者: [Takashima, Seiji, Kanatsu-Shinohara, Mito, Shinohara, Takashi]
通讯作者: Shinohara, Takashi
6
    Study on quinone dimer formation and redox disproportionation in plant polyphenol metabolism
    • 批准号:
      20K07102
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.5万
    • 财政年份:
      2020
    • 负责人:
      TANAKA Takashi
    • 依托单位:
    An approach to neural circuit reconstruction after brain injury targeting inflammation in the brain in elderly mice
    • 批准号:
      17K13079
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.58万
    • 财政年份:
      2017
    • 负责人:
      TANAKA Takashi
    • 依托单位:
    Chemical study on non-enzymatic oxidation-reduction dismutation of plant polyphenol and verification of the generality
    • 批准号:
      17K08338
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2017
    • 负责人:
      TANAKA Takashi
    • 依托单位:
    Integrated research of neural network reorganization following brain injury for clinical application
    • 批准号:
      15K16377
    • 项目类别:
      Grant-in-Aid for Young Scientists (B)
    • 资助金额:
      $2.41万
    • 财政年份:
      2015
    • 负责人:
      TANAKA Takashi
    • 依托单位:
    海外基金