Phase III COBRE: Multimodal Imaging of Neuropsychiatric Disorders (MIND)

项目摘要/摘要 此第三阶段(P-III)COBRE项目将扩展我们阶段已成功利用的核心 第一阶段(P-I)和第二阶段(P-II)科布雷项目，并通过国际货币基金组织在新墨西哥州维持这些独特的资源。 商业计划的实施。在过去的八年里，我们建立了基础设施，并创造了一个 边缘脑成像中心，我们的P-II项目刚刚过半，甚至比我们的P-II更成功- 我在这个时间点上。心理研究网络(MRN)拥有一台Elekta Neuromag 306通道脑磁图 系统、高密度脑电实验室、3T西门子Trio核磁共振扫描仪和1.5T西门子Avanto核磁共振 扫描仪。其他资源包括集中的神经信息学系统、强大的IT管理计划以及 最先进的图像分析专业知识和工具。这个P-III科布雷中心将继续我们的势头 将我们开发的核心转移到一个长期可持续的位置。我们将继续进行技术 在P-II项目期间建立的核心包括多模式数据采集(MDA)、算法和数据分析- SIS(ADA)，以及生物统计学和神经信息学(BNI)。这些核心已经开始服务于MRN和更大的 社区以及其他机构，包括与纽约IDEA资助的项目进行广泛合作 墨西哥和其他州。我们相信P-III科布雷处于非常有利的地位，可以建立和维持新的 墨西哥是首屈一指的大脑成像地点之一。我们包括一个广泛的试点项目计划(PPP)， 建立在作为早期科布雷阶段的一部分实施的成功试点计划的基础上。其中包括一位前任- 紧凑的教育、指导和教师发展计划，仔细地指导和定位 利用核心来最大限度地发挥其潜力，成功地竞争外部资金，从而实现最终目标 科布雷计划的目标。 2.

Project Summary/Abstract This Phase III (P-III) COBRE project will extend the cores that have been successfully leveraged in our Phase I (P-I) and Phase II (P-II) COBRE projects and sustain these unique resources in New Mexico through the im- plementation of a business plan. Over the past eight years we have built up infrastructure and created a cutting edge brain imaging center, our P-II project is just over half-way through and is even more successful than our P- I was at this point in time. The Mind Research Network (MRN) houses an Elekta Neuromag 306-channel MEG System, a high density EEG lab, a 3T Siemens Trio MRI scanner, and a mobile 1.5T Siemens Avanto MRI scanner. Additional resources include a centralized neuroinformatics system, a strong IT management plan, and state-of-the-art image analysis expertise and tools. This P-III COBRE center will continue our momentum and move the cores we have developed into a position of long term sustainability. We will continue with the technical cores established during the P-II project including multimodal data acquisition (MDA), algorithm and data analy- sis (ADA), and biostatistics and neuro-informatics (BNI). These cores have begun to serve MRN and the greater community, as well as other institutions including extensive collaborations with IDeA funded projects in New Mexico and other states. We believe this P-III COBRE is extremely well-positioned to establish and sustain New Mexico as one of the premier brain imaging sites. We include an extensive pilot project program (PPP) that is built on the successful pilot programs implemented as part of the earlier COBRE phases. This includes an ex- tensive educational, mentoring, and faculty development program to carefully mentor and position faculty who use the cores to maximize their potential to successfully compete for external funding, thus fulfilling the ultimate goals of the COBRE program. 2