Airborne PCBs: Sources, Exposures, Toxicities, Remediation

空气中多氯联苯：来源、暴露、毒性、修复

• 批准号: 10381933
• 负责人: Keri C Hornbuckle
• 金额: $ 1.12万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-12 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10381933
• 关键词: American; Chemicals; Data; Environment; Familiarity; Federal Government; Goals; Government Agencies; Health; Human; Knowledge; Maps; Outcome; Polychlorinated Biphenyls; Process; Reporting; Research Personnel; Review Literature; Role; Source; Techniques; Toxic effect; Toxicology; chemical property; dashboard; data management; data visualization; externship; insight; pollutant; remediation; screening

Project Description (Abstract) Per- and polyfluoroalkyl substances (PFAS) are contaminants of emerging concern which pose a direct threat to ecological and human health. Since 2019, the EPA Chemical Pollutants Assessment Division (CPAD) has been conducting systematic literature reviews of specific PFAS. The goal of these reviews is to compile the numerous sources of toxicological data describing these compounds and make the data more widely available to other government agencies, researchers, stakeholders, and the American public. The EPA is currently working towards the ambitious goal of reviewing and reporting on over 9,000 PFAS by 2022. The EPA CPAD aims to achieve this goal using "Systematic Evidence Mapping" (SEM) techniques. The proposed K.C. Donnelly externship project would involve the applicant's participation in the screening, data extraction, and data visualization processes required to construct the evidence maps posted on the EPA PFAS dashboard. Outcomes of the externship project for the applicant would include an enhanced familiarity with PFAS' wide-ranging physical-chemical properties and associated toxicological effects; intimate knowledge of the EPA CPAD's SEM process, data management strategies, and data visualization techniques; as well as a greater insight into the role of Federal government in protecting our natural environment.

项目描述（摘要） 全氟烷基和多氟烷基物质（PFAS）是新出现的令人担忧的污染物 对生态和人类健康构成直接威胁。自2019年以来，EPA化学品 污染物评估司（CPAD）一直在进行系统的文献综述， 具体的PFAS。这些评论的目的是汇编众多的毒理学来源， 描述这些化合物的数据，并使数据更广泛地提供给其他 政府机构、研究人员、利益相关者和美国公众。美国环保署正在 目前正在努力实现审查和报告9,000多个PFAS的宏伟目标， 2022. EPA CPAD旨在使用“系统证据图”（SEM）实现这一目标。 技术.拟议的K.C.唐纳利实习项目将涉及申请人的 参与筛选、数据提取和数据可视化过程， 构建发布在EPA PFAS仪表板上的证据图。校外实习的结果 申请人的项目将包括对PFAS广泛的 物理化学特性和相关的毒理学效应; EPA CPAD的SEM流程、数据管理策略和数据可视化技术; 以及更深入地了解联邦政府在保护我们的自然资源方面的作用 环境