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EXTRACELLULAR MATRIX SYNTHESIS BY HUMAN TUMORS IN VITRO

EXTRACELLULAR MATRIX SYNTHESIS BY HUMAN TUMORS IN VITRO
人类肿瘤的体外细胞外基质合成
批准号：
3821218
负责人：
T J TRICHE
金额：
$0.0万
依托单位：
DIVISION OF CANCER BIOLOGY AND DIAGNOSIS
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3821218
关键词：
Ewing's tumor autoradiography carcinoma cell differentiation cellular oncology collagen extracellular matrix fibroblasts fibronectins fibrosarcoma gel electrophoresis human tissue immunofluorescence technique laboratory mouse neoplasm /cancer classification /staging neoplasm /cancer genetics neoplasm /cancer immunodiagnosis neoplastic cell neoplastic growth procollagen protein biosynthesis protein structure radiotracer tissue /cell culture

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中文摘要
翻译
人肿瘤合成基质蛋白的类型和数量 体外培养的细胞似乎与培养的正常细胞平行 在某种程度上是同行。 我们扩大了这些观察 来确定这些模式是否 可能会对肿瘤的起源进行更精确的分类。 此外，我们正在研究一种新的基质蛋白， 被这些肿瘤所感染 身份，功能和分子 该成分的细胞外基质内的组织是 目前未知。
英文摘要
The type and amount of matrix proteins synthesized by human tumor cells in vitro appears to parallel that of cultured normal cell counterparts to some extent. We have broadened these observations to a variety of human tumors to determine whether these patterns might allow more precise categorization of the tumor's origins. In addition, we are characterizing a new matrix protein synthesized by some of these tumors. The identity, function, and molecular organization within the extracellular matrix of this component is currently unknown.
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会议论文
EWING'S SARCOMA--DIFFERENTIATION IN VITRO
A NEW HIGH MOLECULAR WEIGHT EXTRACELLULAR MATRIX PROTEIN
EWING'S SARCOMA--DIFFERENTIATION IN VITRO
EXTRACELLULAR MATRIX SYNTHESIS BY HUMAN TUMORS IN VITRO
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