课题基金 / 基金详情

REGULATION OF THE ANTIBODY RESPONSE TO MICROBIAL POLYSACCHARIDE ANTIGENS

REGULATION OF THE ANTIBODY RESPONSE TO MICROBIAL POLYSACCHARIDE ANTIGENS
微生物多糖抗原抗体反应的调节
批准号：
3821967
负责人：
P J BAKER
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3821967
关键词：
Escherichia coli Streptococcus pneumoniae T lymphocyte antibody formation antibody specificity antigen antibody reaction autoantibody bacterial antigens bacterial polysaccharides genetic regulation hybridomas immune tolerance /unresponsiveness immunogenetics immunoglobulin genes immunologic memory immunoregulation immunosuppressive leukocyte activation /transformation lipopolysaccharides microorganism immunology suppressor T lymphocyte surface antigens

项目摘要

项目成果

P J BAKER的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Although prior treatment with subimmunogenic amounts of some preparations of bacterial lipopolysaccharide (LPS) results in the development of immunological memory, prior exposure to others results in profound unresponsiveness or suppression. The results of preliminary experiments suggest that the later may be mediated by a subset of T cells possessing the Lyt2 cell-surface antigen. Extracts of mannan derived from Candida albicans can both enhance and suppress antibody responses to unrelated antigen. These immunomodulatory effects can be separated on the basis of molecular size and charge, indicating that they are mediated by distinct components present in extracts of mannan.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
MODE OF ACTION OF THYMUS DERIVED (T) SUPPRESSOR AND AMPLIFIER CELLS
海外基金