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REGULATION OF THE ANTIBODY RESPONSE TO MICROBIAL POLYSACCHARIDE ANTIGENS

REGULATION OF THE ANTIBODY RESPONSE TO MICROBIAL POLYSACCHARIDE ANTIGENS
微生物多糖抗原抗体反应的调节
批准号：
4688364
负责人：
P J BAKER
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4688364
关键词：
Escherichia coli Streptococcus pneumoniae T lymphocyte antibody formation antibody specificity autoantibody bacterial antigens bacterial polysaccharides genetic regulation hybridomas immune tolerance /unresponsiveness immunogenetics immunoglobulin genes immunologic memory immunoregulation immunosuppressive leukocyte activation /transformation lipopolysaccharides microorganism immunology suppressor T lymphocyte

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英文摘要
Mannans can produce either stimulation or suppression of the antibody response to Type III pneumococcal polysaccharide (SSS-III) and sheep erythrocytes (SRBC); the effect produced depends upon the concentration, molecular size, and chemical composition of the preparation of mannan used. These immuno modulatory effects appear to be T cell dependent since they are not demonstrable in athymic nude mice and the mannans used do not induce the non-specific proliferation of B lymphocytes.
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GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
REGULATION OF THE ANTIBODY RESPONSE TO MICROBIAL POLYSACCHARIDE ANTIGENS
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