BIOPHYSICAL INSTRUMENTATION AND METHODOLOGY

该项目旨在开发新的仪器和方法， 并改进现有的仪器和技术， 生物大分子的表征及其研究 交互. 分析超浓缩技术， 辅助它，以及使用数学的数据分析方法 适用于这些技术的建模是 兴趣 研究继续应用数学建模， 超离心分析的问题，以及新的 进行实验和分析数据的方法。 1994年报告 描述了一种新的实验方法的发展 以及分析用于蛋白质-核酸分析的数据， 蛋白质相互作用 这方面的工作继续进行， 强调开发更快，更容易的方法使用MLAB。 其他 信号处理的应用研究已经开始 和图像增强技术来进行超精细数据分析。

The project is intended to develop new instrumentation and methods, and to improve existing instrumentation and techniques, for the characterization of biological macromolecules and the study of their interactions. Analytical ultracentrifugation, the techniques ancillary to it, and methods of data analysis using mathematical modeling appropriate for these techniques are the major areas of interest. Studies have continued on the application of mathematical modeling to problems of ultracentrifugal analysis, and on the development of new methods of performing experiments and analyzing data. The 1994 report described the development of a new method of performing experiments and analyzing data for the analysis of protein-nucleic acid and protein-protein interactions. Work in this area has continued, with emphasis on developing faster and easier methods of using MLAB. Other studies have been initiated on the application of signal processing and image enhancement techniques to ultracentrifugal data analysis.