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PURINE NUCLEOSIDE PHOSPHORYLASE & NEW CHEMOTHERAPIES FOR LYMPHOMA & GRAFT REJECT

PURINE NUCLEOSIDE PHOSPHORYLASE & NEW CHEMOTHERAPIES FOR LYMPHOMA & GRAFT REJECT
嘌呤核苷磷酸化酶
批准号：
6205796
负责人：
STEVE ALMO
金额：
$0.0万
依托单位：
ALBERT EINSTEIN COLLEGE OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-09-01 至 2000-08-31
来源：
https://reporter.nih.gov/project-details/6205796
关键词：
biological products biomedical resource enzymes spectrometry synchrotrons

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英文摘要
The following structures have been solved or datasets collected: apo-Guanylate Kinase: Hg MAD data at 2.0 A, four wavelengths. Structure has been solved by MAD phasing and the refinement at 1.8 A is in progress. ERA GTPase: SeMet MAD data at 3.2 A, four wavelengths. We were not able to solve for the 16 Se sites due to the low resolution and low signal/noise ratio. ERA GTPase: native data at 2.6 A. apo-Guanylate Kinase: native data at 1.8 A. ERA GTPase: Hg MAD data at 2.6 A, four wavelengths. MAD phases have a FOM of 0.60 before solvent flattening. Tracing is in progress.
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