MICROARRAY EXPLORER FOR THE DATA MINING OF EXPRESSION PROFILES OF CDNA MICROARRAY

MicroArray Explorer（MAExplorer）是一种基于Web的cDNA微阵列数据库探索性数据分析工具，用于分析来自小鼠乳腺基因组计划（http：//mammary.nih.gov/mgap）的数据。它是一个运行在用户Web浏览器中的Java applet。它允许在多个微阵列上进行定量cDNA表达谱的探索性数据分析。数据可以被过滤，查看和直接操作的图像，散点图，直方图，表达谱图，聚类分析等克隆或阵列的报告可以产生与网络访问UniGene，GeneBank和其他互联网数据库。报告也可以导出到Excel。阵列用于监测各种生理条件下的表达谱。在这一点上，表达谱已经从正常乳腺发育的几个阶段和不同的肿瘤模型中获得。使用此程序，您可以：1）分析单个基因的表达; 2）分析基因家族和簇的表达; 3）比较表达模式。根据需要将数据下载到用户的Web浏览器，以便在用户的计算机上进行实时分析。1998年12月1日至1999年9月30日Z 01 BC 10303-01 - cDNA，microarray，data mining，breast，Web，gene expression，- Neither Human Subjects nor Human Tissues

The MicroArray Explorer (MAExplorer) is a Web-based cDNA microarray database exploratory data analysis tool called for analyzing data from the Mouse Mammary Genome Project (http://mammary.nih.gov/mgap). It is a Java applet which runs in a users Web browser. It allows the exploratory data analysis of quantitative cDNA expression profiles across multiple microarrays. Data may be filtered, viewed and directly manipulated in images, scatter plots, histograms, expression profile plots, cluster analysis, etc. Reports on clones or arrays may be generated with Web access to UniGene, GeneBank and other Internet databases. Reports may also be exported to Excel. Arrays are used to monitor expression profiles under various physiological conditions. At this point expression profiles have been obtained from several stages of normal mammary gland development and different tumor models. With this program, you may: 1) analyze the expression of individual genes; 2) analyze the expression of gene families and clusters; and 3) compare expression patterns. Data is downloaded as required to the users Web browser to perform real-time analyses on the users computer. However, the user has access to the entire database and may save and share their explorations in a groupware environment.December 1, 1998 through September 30, 1999Z01 BC 10303-01 - cDNA, microarray, data mining, breast, Web, gene expression, - Neither Human Subjects nor Human Tissues