BIVISTA: multi-modality imaging for improving surgical intervention

胰腺癌和乳腺癌等主要癌症(全球发病率分别超过277,000和1,383,000)依赖手术干预。挑战是通过介入成像技术降低上述和其他类型癌症的死亡率，这种技术可以在手术时帮助临床医生和外科医生。临床诊断是改善患者管理的基础，我们建议在护理点进行高质量的成像将有助于改善患者的诊断和治疗结果。伽马相机通常用于医学的许多领域，通过向患者体内注射放射性“示踪剂”化合物来成像不同的组织类型和过程。所得到的图像对于临床医生在各种疾病的分期和治疗中具有重要价值。结合BIVISTA系统固有的多光谱成像，将改进对各种癌症和其他疾病的诊断和治疗管理。关于BIVISTA概念的专利申请已经提交。与大视野伽马相机相比，BIVISTA的优势包括：独特地结合了伽马和光学成像，分辨率高得多，允许对较小区域的组织进行成像或研究其他过程，如淋巴引流，紧凑型和移动设备提供可在各种环境中使用的实时成像，例如在床边和手术室。多模式成像：同时使用光学和伽马射线以及绘制荧光标记图的能力；外科实践中的一项新兴技术。患者体内活动三维分布的高空间分辨率信息BIVISTA将为一系列患者提供显著的医疗保健益处。

Major cancers such as pancreatic and breast cancer (worldwide incidence of over 277,000 and 1,383,000 respectively) rely on surgical intervention. The challenge is to reduce the mortality rate for these and other types of cancer through interventional imaging techniques that can assist clinicians and surgeons at the time of operation. Clinical diagnosis forms the basis for improved patient management and we propose that high quality imaging at the point of care will contribute to better diagnosis and treatment outcomes for patients.Gamma cameras are used routinely in many areas of medicine to image different tissue types and processes using radioactive 'tracer' compounds injected into the patient. The resulting images are of great value to the clinician in the staging and treatment of a variety of conditions. The combination of multi-spectral imaging, inherent in the BIVISTA system, will improve diagnosis and hence treatment management in a wide variety of cancers and other diseases. A patent application has been filed on the BIVISTA concept. The advantages of the BIVISTA versus larger-field gamma cameras include: Uniquely combines gamma and optical imaging Much higher resolution which allows imaging of smaller areas of tissue or the study of other processes such as lymph drainage Compact and mobile device offering real time imaging that can be used in a variety of environments, for example at the bedside and in the operating theatre. Multi-modality imaging: simultaneous optical and gamma ray and the ability to map fluorescence markers; an emerging technology in surgical practice. High spatial resolution information of 3D distribution of activity within the patientBIVISTA will deliver significant healthcare benefits to a range of patients.