Multi-ethnic Study Of Atherosclerosis - Vision Component

多种族动脉粥样硬化研究（梅萨）是一项多中心、队列研究，其中对6，814名45-84岁患有亚临床心血管疾病的高加索人、西班牙人、非洲裔美国人和亚裔美国人男性和女性进行了10年随访，以确定进展为明显心血管疾病的预测因素。梅萨研究由NHLBI赞助，并根据合同提供资金。 博士Cotch是MESA-EYE组件（屈光和眼底摄影）的合作者。作为第第二台面访视的一部分，从2002年9月开始，眼部部分的目的是记录视网膜微血管变化的存在和严重程度（从数字视网膜照片中解释），这些变化表明黄斑变性和糖尿病视网膜病变，并描述它们与微血管和大血管系统性疾病的横截面和纵向测量的相互关系。视力/客观屈光部分将允许我们按性别和种族估计视力损害，确定通过更好的屈光矫正可以减少视力损害的程度，并将视觉结果与视网膜病理学相关联。 于本财政年度，已制定及实施质量控制程序。数据管理工作正在进行中。截至2003年8月，4736名梅萨参与者完成了眼部部分。预计下一财政年度将完成对中东和梅萨地区所有成员的第第二台面次访问。预计在几个月后可提供数据用于分析目的。

The Multi-Ethnic Study of Atherosclerosis (MESA) is a multicenter, cohort study in which a population-based sample of 6,814 Caucasian, Hispanic, African-American and Asian-American men and women aged 45-84 with subclinical cardiovascular disease are followed for 10 years to identify factors predictive of progression to overt cardiovascular disease. The MESA study is sponsored by NHLBI and is funded under contract. Dr. Cotch is a collaborator in the MESA-EYE component (refraction and fundus photography). Part of the second MESA visit and beginning in September 2002, the aims of the ocular component are to document the presence and severity of retinal microvascular changes (as interpreted from digital retinal photos) indicative of macular degeneration and diabetic retinopathy, as well as to describe their interrelationships with cross-sectional and longitudinal measures of microvascular and macrovascular systemic disease. The visual acuity/objective refraction component will allow us to estimate visual impairment by sex and ethnicity, determine the degree to which visual impairment could be reduced with better refractive correction, and correlate visual findings with retinal pathology. During this fiscal year, quality control procedures were developed and implemented. Data management activites are underway. As of August 2003, 4736 MESA participants completed the ocular component. The projected completion of the second MESA visit for all members of the MESA cohort is scheduled to occur next fiscal year. Data are projected to be available for analytic purposes a few months thereafter.