WV-INBRE:APPALACHIAN CARDIOVASCULAR RESEARCH NETWORK (ACORN)

描述(由申请者提供)：西弗吉尼亚州已被指定为获得国家卫生研究院拨款的成功率历史上最低的州。马歇尔大学(MU)与西弗吉尼亚大学(VVVU)合作，获得了生物医学研究基础设施网络(BRIN)奖，以开始建立合作努力，资助西弗吉尼亚大学本科院校的研究。目前的WV-INBRE(IDEA Networks Of Biomedical Research Experence)应用将建立在WV-Brin奖的成功基础上。为此，墨尔本大学将与西弗吉尼亚大学合作，作为一个由八个本科生机构组成的研究网络的牵头机构。该网络的多学科研究主题将是细胞和分子生物学，重点是心血管疾病。有六个研究项目的四个本科生机构被确定为完整的网络研究机构(NRI)，一个机构被指定为过渡性NRI，三个机构被指定为网络扩展机构(NOIS)。这些学校共同构成了西弗吉尼亚大学研究网络的核心。已经建立了行政、生物信息学和外联核心，以促进国家研究机构和国家创新研究所的科学家和学生的研究进展、指导和培训以及职业发展。在WVBRIN期间开发的成功的阿巴拉契亚心血管研究网络(ACCON)将扩大范围。计划旨在为本科生提供研究机会，这将有助于为这些学生提供进入健康相关研究职业的管道。将开展大量活动，扩大与国家创新机构的联系，以增强其成为国家创新倡议的潜力。此外，通过提供大量研讨会、州内和州外科学家的研讨会、研究培训和指导以及使用最先进的核心设施，WV-INBRE将有助于增强WV员工的科学和技术知识基础。

DESCRIPTION (provided by applicant): West Virginia has been designated as a State that has a historically low success rate in obtaining grant awards from the National Institutes of Health. Marshall University (MU), in partnership with West Virginia University (VVVU), was awarded a Biomedical Research Infrastructure Network (BRIN) award to begin to build a collaborative effort to sponsor research at WV undergraduate institutions. The current WV-INBRE (IDEA Networks of Biomedical Research Excellence) application will build on the foundation of the successes of the WV-BRIN award. To this end, MU, in partnership with WVU, will serve as lead institutions to a research network consisting of eight undergraduate institutions. The multi-disciplinary research theme for this network will be cellular and molecular biology with an emphasis on cardiovascular disease. Four undergraduate institutions with six research projects have been identified as full Network Research Institutions (NRI), one institution has been designated a transitional NRI, and three insitutions have been desginated Network Outreach Institutions (NOIs). Collectively, these schools comprise the heart of the WV research network. Administrative, Bioinformatics and Outreach Cores have been established to facilitate the research progress, mentoring and training, and career development of scientists and students at the NRIs and NOIs. The successful Appalachian Cardiovascular Research Network (ACoRN) developed during WVBRIN will be expanded in scope. Programs are proposed to provide research opportunities for undergraduates students that will help serve as a pipeline for these students into health related research careers. Significant activity in outreach to NOIs will be made to enhance their potential to becoma a NRI. In addition, through providing numerous workshops, seminars from in-state and out-of-state scientists, research training and mentoring, and access to state-of-the-art core facilities, WV-INBRE will help enhance the science and technology knowledge base of the WV workforce.