Pilot Projects - Autonomic Rare Diseases Clinical Research Consortium

试点项目 - 自主神经罕见疾病临床研究联盟

• 批准号: 8380488
• 负责人: D S GOLDSTEIN
• 金额: $ 7.55万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8380488
• 关键词: Aldosterone; Attenuated; Autonomic nervous system disorders; Biological Assay; Blood Plasma Volume; Blood Pressure; Carbidopa; Cardiovascular system; Catecholamines; Clinical; Clinical Research; Clinical Trials; Data; Development; Diuretics; Dopamine; Drops; Excretory function; Hearing; Heart Rate; Hypovolemia; Hypovolemics; Institution; Instruction; Intervention; Kidney; Lead; Mediating; Movement; Oral; Patients; Pharmaceutical Preparations; Pilot Projects; Plasma; Rare Diseases; Regulation; Renin; Research Personnel; Schedule; Sodium; Symptoms; Syndrome; Tachycardia; Teleconferences; Testing; Therapeutic; design; healthy volunteer; instrument; meetings; response; urinary

PILOT PROJECT SUMMARY (See instructions): Through the pilot component of the Autonomic RDCRC, the five institutions comprising this Consortium will collaborate in the choice and conduct of pilot projects, designed to take advantage of new clinical research opportunities in Rare Autonomic Disorders. As the investigators hear of promising new developments in the autonomic field, they will share these with their Consortium co-investigators. Upon discussion by teleconference or at one of the scheduled Consortium meetings.Jhe top management people from each institution may then propose to conduct a pilot study. The focus of a pilot study may be the development of a new assay or clinical instrument, or it could be an assessment of the therapeutic potential of a new medication.

试点项目总结（参见说明）： 通过自主RDCRC的试点部分，组成该联盟的五个机构将合作选择和开展试点项目，旨在利用罕见自主神经疾病的新临床研究机会。当研究人员听到自主领域有希望的新发展时，他们将与他们的联盟合作研究人员分享这些发展。在通过电话会议或预定的联合会会议讨论后，每个机构的高层管理人员可以提议进行试点研究。试点研究的重点可能是开发新的检测或临床仪器，也可能是评估新药的治疗潜力。