VISUAL RESTORATION AFTER RETINAL TRANSPLANTATION

视网膜移植后的视力恢复

• 批准号: 8362637
• 负责人: ZHONGPING CHEN
• 金额: $ 0.31万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8362637
• 关键词: Animals; Biotechnology; Equipment; Funding; Grant; Human Resources; Image; Lasers; Life; National Center for Research Resources; Principal Investigator; Rattus; Research; Research Infrastructure; Resources; Retinal; Source; Suid Herpesvirus 1; Testing; Transplantation; United States National Institutes of Health; Visual; cost; fetal; human embryonic stem cell line; human tissue; restoration; retina transplantation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The aim of this collaborative study with the BLI is to image retinal transplants in live animals to be able to select successful transplants for further testing. The transplants imaged by OCT will either be derived from fetal (rat or human) tissue, or from NIH-approved human embryonic stem cell (hESC) lines. No rats infected with pseudorabies virus or any other zoonotic agent will be imaged at BLI or involve BLI personnel or equipment.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 这项与 BLI 合作研究的目的是对活体动物的视网膜移植进行成像，以便能够选择成功的移植物进行进一步测试。 通过 OCT 成像的移植物要么来自胎儿（大鼠或人类）组织，要么来自 NIH 批准的人类胚胎干细胞 (hESC) 系。 感染伪狂犬病病毒或任何其他人畜共患病原体的老鼠不会在 BLI 进行成像，也不会涉及 BLI 人员或设备。