Promoting Cancer-related Behavior Change through Positive Emotions (PQ4)

通过积极情绪促进癌症相关行为改变（PQ4）

基本信息

批准号：
8676748
负责人：
BARBARA LEE FREDRICKSON
金额：
$ 47.43万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-08-08 至 2016-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8676748
关键词：
Adherence Adopted Affect Alcohol consumption Alcohols American Cancer Society Attention Awareness Behavior Behavioral Biological Brain Cardiac Carrots - dietary Chronic Disease Conscious Data Diet Eating Ego Emotional Endocrine Goals Health Health Benefit Health Promotion Health behavior Incidence Individual Individual Differences Inflammation Intervention Knowledge Learning Life Life Style Link Long-Term Effects Love Maintenance Malignant Neoplasms Measures Meditation Mental Depression Modeling Nutritional Outcome Oxytocin Pain Patient Self-Report Personal Satisfaction Physical activity Physiological Placebo Control Positioning Attribute Preventive Process Public Health Randomized Research Resolution Resources Rest Risk Risk Behaviors Role Science Seeds Self-control as a personality trait Stream Stress System Testing Theoretical model Time Tobacco Tobacco use Translating Translational Research Work arm base behavior change biopsychosocial blind cancer risk clinical practice evidence base experience flexibility follow-up improved indexing innovation mindfulness mindfulness meditation novel positive emotional state prevent programs psychologic research study resilience response skills theories trait

项目摘要

DESCRIPTION (provided by applicant): The American Cancer Society estimates that 62% of all cancers could be prevented altogether through lifestyle change. Despite good intentions, people's attempts to alter their behaviors known to increase cancer risk - related to diet, physica activity, tobacco and alcohol use - often fail, which ultimately increases their risks for various cancers. In response to NCI's Provocative Question 4, the overarching goal of the proposed research is to investigate the role of positive emotions in facilitating successful lifestyle chang, defined as long-term adherence to cancer- preventive behaviors (e.g., nutritious eating, physical activity, tobacco, and alcohol use). An innovative upward spiral model of lifestyle change integrates multiple streams of research in basic behavioral and brain sciences to position positive emotions as key active ingredients that not only seed non-conscious motivational pulls toward newly-adopted cancer-preventive behaviors, but also reshape key biopsychosocial resources in ways that increase the subsequent positive emotion yield of multiple cancer-preventive behaviors, creating a self- sustaining dynamic system. A longitudinal, dual-blind, placebo-controlled field experiment tests this new model by targeting three Specific Aims. These aims are: (1) to identify biopsychosocial resources that moderate the link between cancer-preventive behaviors and their positive emotion yield; (2) to test whether and how positive emotions, experienced in daily life, produce a psychological propensity for wellness through the combined presence of (a) increases in non-conscious motives for cancer-preventive behaviors and (b) increases in biopsychosocial resources; and (3) to test whether positive emotions and a psychological propensity for wellness predict increasing and sustained cancer-preventive behaviors and improved health-related outcomes at 18-month follow-up. The proposed study tests the novel upward spiral model in daily life with densely repeated measures and physiological, behavioral, endocrine, and self- report indices of health-related outcomes. This program of translational research stands to reshape public health interventions and unlock hidden opportunities to drastically reduce the incidence of cancer.

描述（由申请人提供）：美国癌症协会估计，所有癌症中有62％可以通过改变生活方式来完全阻止。尽管有良好的意图，但人们试图改变其行为已知以增加癌症风险的行为 - 与饮食，物理活动，烟草和饮酒有关 - 常常失败，最终增加了对各种癌症的风险。为了回应NCI的挑衅性问题4，拟议的研究的总体目标是研究积极情绪在促进成功的生活方式张方面的作用，这被定义为长期遵守癌症预防性行为（例如，营养饮食，体育锻炼，活动，烟草和酒精使用）。一种创新的生活方式变化的上向上螺旋模型整合了基本行为和脑科学中的多种研究，将积极的情绪定位为关键的活跃成分，不仅种子无意识的动机朝着新近培养的癌症预防的行为朝着新的癌症预防行为方向发展，而且还可以将良好的情感效率增强的方式增强，使多种癌症的癌症持续性地增强癌症，从而使多种癌症的癌症能够自我促进。纵向，双盲，安慰剂对照的现场实验通过针对三个特定目标来测试该新模型。这些目的是：（1）确定可以缓解预防癌症行为与其积极情绪产量之间联系的生物心理社会资源；（2）测试日常生活中经历的积极情绪以及如何通过（a）增加无意识的预防癌症行为的动机以及（b）生物心理社会资源的增加而产生心理倾向；（3）测试积极的情绪和心理倾向是否可以预测在18个月的随访中的增加和持续的预防癌症行为，并改善与健康相关的结果。拟议的研究通过密集的重复措施以及生理，行为，内分泌和自我报告指标的健康相关结局，测试了日常生活中新型的向上螺旋模型。这项翻译研究计划旨在重塑公共卫生干预措施，并解锁隐藏的机会，以大大减少癌症的发生。