Request for a Nikon A1 confocal microscope
索取尼康 A1 共焦显微镜
基本信息
- 批准号:8825158
- 负责人:
- 金额:$ 35.79万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-04-01 至 2016-03-31
- 项目状态:已结题
- 来源:
- 关键词:10 year old14 year oldAreaCommunitiesConfocal MicroscopyCore FacilityElectronsFrustrationFundingHousingImageImage AnalysisInstitutionLightMedicalMedical ResearchMethodsMicroscopeNeckPhotonsResearchResearch PersonnelResearch Project GrantsServicesTimeUnited States National Institutes of HealthUniversitiesbasedetectorinstrumentmedical schoolsoperation
项目摘要
DESCRIPTION (provided by applicant): This request is for funds to purchase a basic single photon Nikon A1 confocal microscope with two GaSP detectors. This instrument will be housed within the Center for Biologic Imaging (CBI) at the University of Pittsburgh School of Medicine. The mandate of this core facility is to provide access to a full range of light and electron optica, image analysis, and morphometric methods to all research groups within the University of Pittsburgh School of Medicine. Confocal microscopy is an essential service provided by the center, the current core use confocal microscopes within the facility are a 4 yr. old Nikon A1R, two Olympus FV1000's (8 and 10 years old) and a 14 year old Olympus fluoview 500, There is a single prime reason for this application: to provide critically needed instrument time to the NIH supported users of the Center for Biologic Imaging. Since the CBI commenced operations 22 years ago, it has become an integral part of the medical research community currently participating in research projects with more than 300 PHS funded groups within the medical area, as well as in PHS supported projects with investigators in other departments and at neighboring institutions. The PHS funded user base within the institution continues to expand, and a lack of available confocal time has become a major limiting factor in the utility of the center, this leads to considerable frustration amongst users. The acquisition of a basic single photon confocal microscope will be a tremendous addition to the activity and functionality of the center and will help alleviate the current user bottle neck for single photon confocal microscopy.
描述(由申请人提供):此申请是为了获得资金,以购买一个带有两个喘气探测器的基本单光子尼康A1共聚焦显微镜。该仪器将被安置在匹兹堡大学医学院的生物成像中心(CBI)内。这一核心设施的任务是向匹兹堡大学医学院内的所有研究小组提供全方位的光和电子光学、图像分析和形态测量方法。共焦显微镜是该中心提供的一项基本服务,目前该设施内核心使用的共焦显微镜已有4年之久。老尼康A1R,两台奥林巴斯FV1000的S(8岁和10岁)和一台14岁的奥林巴斯FluoView 500,这一应用的主要原因只有一个:为NIH支持的生物成像中心的用户提供急需的仪器时间。自22年前开始运作以来,CBI已经成为医学研究界不可或缺的一部分,目前它参与了医疗领域内300多个PHS资助团体的研究项目,以及与其他部门和邻近机构的研究人员共同参与的PHS资助项目。该机构内由小灵通资助的用户基础继续扩大,缺乏可用的协调时间已成为该中心效用的一个主要限制因素,这导致用户相当沮丧。基本单光子共焦显微镜的获得将极大地增加该中心的活动和功能,并将有助于缓解目前用户对单光子共焦显微镜的瓶颈。
项目成果
期刊论文数量(13)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
ISSLS prize in basic science 2021: a novel inducible system to regulate transgene expression of TIMP1.
2021年ISSLS基础科学奖:一种调节TIMP1转基因表达的新型诱导系统
- DOI:10.1007/s00586-021-06728-0
- 发表时间:2021-05
- 期刊:
- 影响因子:0
- 作者:Han Y;Ouyang Z;Wawrose RA;Chen SR;Hallbaum M;Dong Q;Dando E;Tang Y;Wang B;Lee JY;Shaw JD;Kang JD;Sowa GA;Vo NN
- 通讯作者:Vo NN
Pathway crosstalk enables cells to interpret TGF-β duration.
- DOI:10.1038/s41540-018-0060-5
- 发表时间:2018
- 期刊:
- 影响因子:4
- 作者:Zhang J;Tian XJ;Chen YJ;Wang W;Watkins S;Xing J
- 通讯作者:Xing J
Arsenic disrupts extracellular vesicle-mediated signaling in regenerating myofibers.
砷会破坏肌纤维再生过程中细胞外囊泡介导的信号传导。
- DOI:10.1093/toxsci/kfad075
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Clemens,Zachary;Wang,Kai;Ambrosio,Fabrisia;Barchowsky,Aaron
- 通讯作者:Barchowsky,Aaron
Age-dependent changes in intervertebral disc cell mitochondria and bioenergetics.
- DOI:10.22203/ecm.v036a13
- 发表时间:2018-10-18
- 期刊:
- 影响因子:3.1
- 作者:
- 通讯作者:
MicroRNA-23a downregulates the expression of interferon regulatory factor-1 in hepatocellular carcinoma cells.
- DOI:10.3892/or.2016.4864
- 发表时间:2016-08
- 期刊:
- 影响因子:4.2
- 作者:Yan Y;Liang Z;Du Q;Yang M;Geller DA
- 通讯作者:Geller DA
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SIMON C WATKINS的其他文献
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{{ truncateString('SIMON C WATKINS', 18)}}的其他基金
Request for transmission electron microscope for the University of Pittsburgh
匹兹堡大学申请透射电子显微镜
- 批准号:
8447178 - 财政年份:2013
- 资助金额:
$ 35.79万 - 项目类别:
Request for a Structured Illumination Super-Resolution Microscope
请求结构照明超分辨率显微镜
- 批准号:
8437557 - 财政年份:2013
- 资助金额:
$ 35.79万 - 项目类别:
Request for Zeiss 710 multiphoton 5Live Duoscan Microscope
索取蔡司 710 多光子 5Live Duoscan 显微镜
- 批准号:
7827587 - 财政年份:2011
- 资助金额:
$ 35.79万 - 项目类别:
Request for live cell confocal microscope for BSL3 facility
请求为 BSL3 设施提供活细胞共聚焦显微镜
- 批准号:
7787740 - 财政年份:2010
- 资助金额:
$ 35.79万 - 项目类别:
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