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Request for a Nikon A1 confocal microscope

索取尼康 A1 共焦显微镜

基本信息

批准号：
8825158
负责人：
SIMON C WATKINS
金额：
$ 35.79万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-04-01 至 2016-03-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): This request is for funds to purchase a basic single photon Nikon A1 confocal microscope with two GaSP detectors. This instrument will be housed within the Center for Biologic Imaging (CBI) at the University of Pittsburgh School of Medicine. The mandate of this core facility is to provide access to a full range of light and electron optica, image analysis, and morphometric methods to all research groups within the University of Pittsburgh School of Medicine. Confocal microscopy is an essential service provided by the center, the current core use confocal microscopes within the facility are a 4 yr. old Nikon A1R, two Olympus FV1000's (8 and 10 years old) and a 14 year old Olympus fluoview 500, There is a single prime reason for this application: to provide critically needed instrument time to the NIH supported users of the Center for Biologic Imaging. Since the CBI commenced operations 22 years ago, it has become an integral part of the medical research community currently participating in research projects with more than 300 PHS funded groups within the medical area, as well as in PHS supported projects with investigators in other departments and at neighboring institutions. The PHS funded user base within the institution continues to expand, and a lack of available confocal time has become a major limiting factor in the utility of the center, this leads to considerable frustration amongst users. The acquisition of a basic single photon confocal microscope will be a tremendous addition to the activity and functionality of the center and will help alleviate the current user bottle neck for single photon confocal microscopy.

描述(由申请人提供)：此申请是为了获得资金，以购买一个带有两个喘气探测器的基本单光子尼康A1共聚焦显微镜。该仪器将被安置在匹兹堡大学医学院的生物成像中心(CBI)内。这一核心设施的任务是向匹兹堡大学医学院内的所有研究小组提供全方位的光和电子光学、图像分析和形态测量方法。共焦显微镜是该中心提供的一项基本服务，目前该设施内核心使用的共焦显微镜已有4年之久。老尼康A1R，两台奥林巴斯FV1000的S(8岁和10岁)和一台14岁的奥林巴斯FluoView 500，这一应用的主要原因只有一个：为NIH支持的生物成像中心的用户提供急需的仪器时间。自22年前开始运作以来，CBI已经成为医学研究界不可或缺的一部分，目前它参与了医疗领域内300多个PHS资助团体的研究项目，以及与其他部门和邻近机构的研究人员共同参与的PHS资助项目。该机构内由小灵通资助的用户基础继续扩大，缺乏可用的协调时间已成为该中心效用的一个主要限制因素，这导致用户相当沮丧。基本单光子共焦显微镜的获得将极大地增加该中心的活动和功能，并将有助于缓解目前用户对单光子共焦显微镜的瓶颈。