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Clinical Trials Network: Southwest Node

临床试验网络：西南节点

基本信息

批准号：
8708012
负责人：
BARBARA S MCCRADY
金额：
$ 109.57万
依托单位：
UNIVERSITY OF NEW MEXICO
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
起止时间：
2002-09-30 至 2017-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8708012
关键词：
Accident and Emergency department Adolescent Alcoholism American American Indians Area Award Behavior Therapy Budgets Buprenorphine Clinical Clinical Sciences Clinical Trials Clinical Trials Network Collaborations Communication Counseling Data Dental Development Drug Addiction Drug abuse Drug usage Educational workshop Evaluation Evidence based practice Family Funding Grant HIV/STD Hispanics Human Resources Human immunodeficiency virus test Individual Intervention Lead Leadership Life Link Location Medical Methamphetamine Methods Minority Mission Naloxone National Institute of Drug Abuse Native Americans New Mexico Occupations Opiate Addiction Opioid Outcome Outpatients Participant Patient Education Pharmaceutical Preparations Pharmacotherapy Population Principal Investigator Procedures Protocols documentation Psychiatric therapeutic procedure Recording of previous events Recruitment Activity Rehabilitation therapy Research Research Activity Research Infrastructure Research Personnel Running Science Services Site Structure Substance Addiction Substance abuse problem Surveys Training Treatment outcome Underserved Population United States Universities Work addiction cost experience follow-up improved innovation meetings member men&apos s group methadone maintenance motivational enhancement therapy multi-site trial pregnant programs protocol development public health relevance quality assurance rural area safer sex screening skills substance abuse treatment treatment program urban area young adult

项目摘要

DESCRIPTION (provided by applicant): Since joining the NIDA Clinical Trials Network in 2002, the Southwest Node has made a substantial and singular contribution to the research activities of the CTN. The Southwest Node has successfully completed six multi-site trials, as well two studies focusing on Native Americans, two survey studies, and several ancillary and platform Studies. We are currently serving as Lead Node for CTN 0047, Screening, Motivational Assessment, and Referral for Treatment in Emergency Departments (SMART-ED). Beyond participation in protocols, the Node has been highly productive in the areas of protocol development, training, committee work, and dissemination. The Node has made an outstanding contribution to advancing the clinical science of addictions treatment in minority and other underserved populations. Of the multi-site trial participants recruited at the Southwest Node, 71% were Hispanic and 7% were Native American, not counting 427 participants thus far in the two Native American protocols. The Node has managed grant funds prudently and efficiently, requesting and spending only what is necessary to achieve our scientific objectives. For the renewal period, the Southwest Node will consist of its RRTC, the University of New Mexico Center on Alcoholism, Substance Abuse, and Addictions (CASAA), and affiliated investigators at the University of New Mexico; 5 primary CTPs, all of which have already collaborated extensively with Node investigators; and 6 secondary CTPs representing a wide range of medical, dental, and psychiatric treatment settings. Strengths of the Southwest Node include: 1) a well-established track record of clinical trials with both behavioral treatments and pharmacotherapies; 2) longstanding experience in the development and evaluation of innovative treatments for addictions; 3) extensive experience with minority and other underserved populations, and demonstrated ability to recruit them; 4) expertise in research on dissemination and training; and 5) geographic representation of the American Southwest. Our agenda for the renewal period will build on our strengths, with four proposed foci of research leadership: 1) implementing addiction treatment in medical settings; 2) optimizing addiction treatment for minority populations; 3) using the family to enhance treatment outcome; and 4) pharmacologic treatment of opioid dependence.

描述(申请人提供)：自2002年加入NIDA临床试验网络以来，西南节点为CTN的研究活动做出了重大而独特的贡献。西南节点已经成功地完成了六项多点试验，以及两项以美洲原住民为重点的研究，两项调查研究，以及几项辅助和平台研究。我们目前是CTN 0047、筛查、激励评估和急诊科转诊(SMART-ED)的牵头节点。除了参与协议之外，该节点还在协议制定、培训、委员会工作和传播方面卓有成效。该节点为促进少数群体和其他服务不足人群成瘾治疗的临床科学做出了杰出贡献。在西南节点招募的多点试验参与者中，71%是西班牙裔，7%是美洲原住民，这还不包括迄今为止在两个美洲原住民方案中的427名参与者。该节点谨慎而高效地管理赠款资金，只申请和使用实现我们的科学目标所需的资金。在续期期间，西南节点将包括其RRTC、新墨西哥大学酒精中毒、药物滥用和成瘾中心(CASAA)和新墨西哥大学的附属调查人员；5个初级CTP，所有这些都已经与Node调查人员广泛合作；以及6个二级CTP，代表广泛的医疗、牙科和精神治疗环境。西南节点的优势包括：1)在行为疗法和药物疗法方面都有良好的临床试验记录；2)在开发和评估针对成瘾的创新疗法方面有长期的经验；3)对少数族裔和其他服务不足的人群有丰富的经验，并显示出招募他们的能力；4)在传播和培训研究方面的专业知识；以及5)美国西南地区的地理代表性。我们在更新期的议程将以我们的优势为基础，提出四个研究领导重点：1)在医疗环境中实施成瘾治疗；2)优化少数群体的成瘾治疗；3)利用家庭改善治疗结果；以及4)阿片类药物依赖的药物治疗。