Leptin as a natural regulator of TFH cell differentiation and vaccination response
Leptin as a natural regulator of TFH cell differentiation and vaccination response
批准号:
nhmrc : 1147769
负责人:
A/Pr Di Yu
金额:
$39.67万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31
中文摘要
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英文摘要
Follicular helper T (Tfh) cells constitute a CD4+ T cell subset that plays an instrumental role to support protective antibody responses in infection and vaccination. Although malnutrition is associated with poor vaccine responses and increased risks of infections, the mechanism is poorly understood. We will investigate the mechanism by which leptin, a hormone secreted by adipose cells, regulates Tfh cell function and vaccination response.
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依托单位:
Leptin as a natural regulator of TFH cell differentiation and vaccination response
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国内基金
海外基金
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