HIV-1 AND ENDOTHELIAL FUNCTION

HIV-1 和内皮功能

• 批准号: 7719564
• 负责人: Christopher J de Souza
• 金额: $ 2.97万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719564
• 关键词: Blood Clot; Blood Vessels; Blood coagulation; Cell Line; Cell physiology; Computer Retrieval of Information on Scientific Projects Database; Endothelial Cells; Funding; Grant; HIV-1; Heart; Individual; Infection; Institution; Link; Purpose; Research; Research Personnel; Resources; Risk; Source; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Individuals with HIV-1 infection demonstrate an increased risk for heart attach. Endothelial cells line blood vessels and help them to dilate and release substances that break down blood clots. A reduction in these functions have been linked to an increased risk of heart attach. The purpose of this study is to determine whether endothelial cell function is reduced in individuals with HIV-1 infection.

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 感染艾滋病毒-1的人患心脏附着的风险增加。内皮细胞排列血管，帮助血管扩张和释放分解血栓的物质。这些功能的降低与心脏附着症风险的增加有关。这项研究的目的是确定感染HIV-1的个体的内皮细胞功能是否降低。