HIV Vaccines

艾滋病毒疫苗

• 批准号: 7930431
• 负责人: ANDREW D ROBERTSON
• 金额: $ 1.5万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-01 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7930431
• 关键词: AIDS Vaccines; Acquired Immunodeficiency Syndrome; Address; Adenoviruses; Alberta province; Canada; Clinical Trials; Collaborations; Communities; Consensus; Development; Fertilization; Fostering; Future; HIV; HIV vaccine; Human; Immune response; Immune system; Immunity; Immunologist; Immunology; Infection; Joints; Lead; Pathogenesis; Prevention; Renaissance; Research Personnel; Science; Scientist; Vaccine Research; Vaccines; Viral; Virus Diseases; innovation; insight; meetings; novel; public health priorities; sobriety; symposium; vaccine candidate; vaccinology; ward

DESCRIPTION (provided by applicant): This proposal is to request support for a Keystone Symposia meeting entitled "HIV Vaccines", organized by Wayne C. Koff, Lynn Morris and Marcus Altfeld, which will be held in Banff, Alberta, Canada from March 21-26, 2010. Recent clinical trials, and in particular the STEP trial of Merck's adenovirus AIDS vaccine candidate, have produced results disappointing to the AIDS vaccine field generally, and have given rise to the sobering realization that the majority of vaccine candidates currently under development are unlikely to provide a truly effective AIDS vaccine. Hence there is now a broad consensus that the field needs to return to some fundamentals of immunology, and addressing how the human (and simian) immune system interacts with HIV and what will be required in an effective immune response against HIV to ward off establishment of infection. To stimulate new insights and approaches to these longstanding problems, Keystone Symposia is offering a novel conference format that facilitates a wider cross-fertilization of ideas among the wider HIV vaccine research community. To that end, the 2010 Keystone Symposia HIV Vaccines meeting will foster innovative ideas and new collaborations between immunology and vaccinology as it pertains to other viral diseases. Traditionally, Keystone Symposia has held concurrent meetings on HIV, integrating vaccines and pathogenesis discussions. For 2010, a new joint symposium of HIV Vaccines in conjunction with Viral Immunity will be convened. These concurrent symposia will greatly encourage cross-fertilization of ideas, allowing AIDS vaccine researchers to interact with viral immunologists who approach immunity from a more fundamental perspective.

DESCRIPTION (provided by applicant): This proposal is to request support for a Keystone Symposia meeting entitled "HIV Vaccines", organized by Wayne C. Koff, Lynn Morris and Marcus Altfeld, which will be held in Banff, Alberta, Canada from March 21-26, 2010. Recent clinical trials, and in particular the STEP trial of Merck's adenovirus AIDS vaccine candidate, have produced results disappointing to the AIDS通常，疫苗场，并引起了人们的意识，即目前正在开发的大多数候选疫苗不太可能提供真正有效的艾滋病疫苗。因此，现在有一个广泛的共识，该领域需要返回某些免疫学基本面，并解决人类（和邻苯二豆）免疫系统如何与HIV相互作用，以及在对HIV的有效免疫反应中需要什么才能阻止建立感染。为了刺激这些长期存在的问题的新见解和方法，Keystone研讨会提供了一种新颖的会议格式，可促进更广泛的HIV HIV疫苗研究社区中更广泛的思想交叉侵占。 为此，2010年的Keystone研讨会HIV疫苗会议将促进与其他病毒疾病有关的免疫学和疫苗学之间的创新思想和新的合作。传统上，Keystone专题讨论会与HIV，整合疫苗和发病机理讨论的并发会议。对于2010年，将召集举办新的HIV疫苗联合研讨会与病毒免疫。这些并发的研讨会将极大地鼓励思想的交叉侵入，使艾滋病疫苗研究人员能够与从更基本的角度接触免疫力的病毒免疫学家互动。