AIDS Clean Cage Storage Facility

艾滋病清洁笼储存设施

• 批准号: 8658314
• 负责人: Jeffrey A Roberts
• 金额: $ 59.64万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-26 至 2017-09-25
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8658314
• 关键词: Acquired Immunodeficiency Syndrome; Animal Housing; Animals; Area; California; Communicable Diseases; Disease; Ensure; Extramural Activities; Funding; Goals; Growth; HIV therapy; HIV vaccine; IACUC; Infectious Diseases Research; Occupational Safety; Primates; Research; Research Facilities Construction Grants; Research Infrastructure; Research Support; Risk; Services; Transportation; Universities; cost; guide for the care and use of laboratory animals; improved; model development; nonhuman primate; operation; research facility; trafficking

DESCRIPTION (provided by applicant): This application from the California National Primate Research Center (CNPRC) located at the University of California, Davis (UCD), seeks to obtain federal funding in the amount of $597,454 through the Limited Competition: Extramural Research Facilities Improvement Program (C06) for the AIDS Clean Cage Storage Facility Project. This request seeks to fund the addition of clean cage storage space necessary to support two new modular animal buildings and existing modular buildings in which AIDS-related and infectious disease research is conducted. This will assure compliance with the Guide for the Care and Use of Laboratory Animals, eighth edition in its directive for clean cage storage to ensure reliable and predictable nonhuman primate (NHP) models for the development of effective HIV vaccines and therapies. The proposed clean cage storage facility is part of a larger plan to segment the CNPRC's indoor animal housing areas into infectious disease and non-infectious disease zones in order to improve occupational safety by eliminating the transportation of caging across major traffic corridors, and improve operational efficiencies. Each zone will have its own indoor animal housing space, cage wash, and clean cage storage facility. The clean cage storage facility is the final component to accomplishing this plan and is integral to the effective and efficient operation of AIDS-related research with the additional capacity of 144 NHPs being provided by the two modular buildings. The specific provisions of this request are as follows: * Clean cage storage capacity for 56 rolling racks (4 cages per rack) * A fully segmented zone for AIDS/ID research and support within the CNPRC The goal of this proposal is to increase the infrastructure capacity necessary to provide cage storage to facilitate growth in AIDS-related research and to improve operational efficiencies that decrease the physical risk and monetary cost of delivering those cages to research.

描述（由申请人提供）：本申请由位于加州大学戴维斯分校 (UCD) 的加州国家灵长类动物研究中心 (CNPRC) 提出，旨在通过有限竞争：艾滋病清洁笼储存设施项目的校外研究设施改进计划 (C06) 获得 597,454 美元的联邦资金。该请求旨在资助增加清洁的笼子存储空间，以支持两个新的模块化动物建筑和现有的进行艾滋病相关和传染病研究的模块化建筑。这将确保遵守《实验动物护理和使用指南》第八版的清洁笼储存指令，以确保可靠且可预测的非人灵长类动物 (NHP) 模型用于开发有效的 HIV 疫苗和疗法。拟议的清洁笼式储存设施是一项更大计划的一部分，该计划将 CNPRC 的室内动物饲养区划分为传染病区和非传染病区，以便通过消除跨主要交通走廊的笼子运输来提高职业安全，并提高运营效率。每个区域都有自己的室内动物饲养空间、笼子清洗和干净的笼子储存设施。干净的笼式储存设施是完成该计划的最后一个组成部分，是艾滋病相关研究有效和高效运作的组成部分，两座模块化建筑还提供了 144 个 NHP 的额外容量。该要求的具体规定如下： * 清洁笼存储容量可容纳 56 个滚动架（每个架 4 个笼子） * CNPRC 内针对 AIDS/ID 研究和支持建立的完全划分的区域 该提案的目标是增加提供笼子存储所需的基础设施容量，以促进艾滋病相关研究的发展，并提高运营效率，从而降低将这些笼子用于研究的物理风险和金钱成本。