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Admin Core

管理核心

基本信息

批准号：
10038235
负责人：
ANGELA L. JEFFERSON
金额：
$ 40.51万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-15 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10038235
关键词：
Academic Medical Centers Advisory Committees Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Alzheimer&apos s disease therapeutic Alzheimer&apos s disease therapy Basic Science Biological Markers Clinical Clinical Research Clinical and Translational Science Awards Collaborations Data Data Storage and Retrieval Development Discipline Disease Pathway Educational workshop Ensure Evaluation Event Faculty Fostering Funding Future Genetic Goals Grant Growth Health Historically Black Colleges and Universities Individual Infrastructure Injury Institutes Investigator-Initiated Research Leadership Link Memory Mission Multi-Institutional Clinical Trial National Institute on Aging Outcome Participant Pathway interactions Pharmacology Policies Positioning Attribute Principal Investigator Protocols documentation Research Research Activity Research Institute Research Personnel Research Training Resource Sharing Resources Science Scientist Site Strategic Planning Structure Techniques Training Activity Translational Research Universities career cohesion cohort cooperative study data exchange data management data sharing early-career faculty graduate student health equity improved medical schools medical specialties meetings neuroimaging next generation novel operation programs ranpirnase repository sharing platform training opportunity undergraduate student vascular contributions

项目摘要

PROJECT SUMMARY – ADMINISTRATIVE CORE The Exploratory Vanderbilt Alzheimer’s Disease Research Center (VADRC) Administrative Core is central to achieving the overall mission of the VADRC and will leverage strong institutional resources to provide excellent administrative oversight for a scalable infrastructure to position Vanderbilt University Medical Center and Vanderbilt University for a future successful P30 application. Under the proven leadership of Dr. Angela Jefferson, supported by Associate Directors, Dr. Consuelo Wilkins and Dr. Charles Sanders, the Administrative Core is uniquely positioned to achieve this goal. Our interdisciplinary Core leadership will ensure that all programmatic objectives of the VADRC are accomplished by coordinating and integrating VADRC Cores and scaling these Center functions into a thriving P30-funded ADRC. Core leadership will drive the Center’s scientific direction emphasizing non-amyloid pathways of injury, including understanding vascular contributions to Alzheimer’s disease and related dementias, discovering novel disease pathways using advanced techniques, and improving pharmacological therapies for Alzheimer’s disease and related dementias. The Administrative Core will serve as the institutional hub for all local Alzheimer’s disease research activities by providing strategic planning, scientific direction, campus-wide integration, and essential infrastructure. Core leadership will identify opportunities for growth while harnessing strengths of existing programs. The Administrative Core will establish and facilitate administrative structure, Center governance, and oversight for Center operations. These functions include managing budgetary oversight, ensuring compliance with regulatory requirements, facilitating ongoing internal and external review and evaluation of VADRC activities, and coordinating fiscal, operational, and regulatory functions to ensure effective utilization of Center resources. The Administrative Core will actively support local research activities and contribute to collaborative national research initiatives and resource sharing to advance the goals of the National Alzheimer’s Project Act. Leadership will establish a scalable data sharing platform to support a future P30 Data Management and Statistical Core. Such infrastructure will promote coordinating and integrating VADRC activities for data transfer that serve local investigator needs and support national research efforts (e.g., National Alzheimer’s Coordinating Center, National Centralized Repository for Alzheimer’s Disease and Related Dementias). Additionally, the Administrative Core will support VADRC participation in multi-site clinical trials. Finally, the Core will be integral in fostering professional development of the next generation of clinicians and scientists in Alzheimer’s disease. Collectively, the VADRC Administrative Core will be instrumental in establishing and facilitating harmonized integration between all Center investigators, collaborators, Core functions, institutional resources, and national partners, which will facilitate a smooth transition to a future P30-funded VADRC.

项目总结-行政核心