Frontiers in Alzheimer's and Aging Research Experiences

项目总结 R25 AG043365-10的续订，适用于美国国家航空航天局的《从本科生到本科生的老龄化研究进展》 教育(ADAR)“计划，现已重新命名：”阿尔茨海默氏症和老龄化研究的前沿“ 经验“(FrA2RE)，请求支持每年≥12有前途的本科生中的五个队列 “…符合条件的…如果他们来自经济、社会、文化或教育方面的不利背景 (响应PAR-20-317)。FrA2RE专注于结构化研究经验和基本 指导在NIA的投资组合中启动和维持职业生涯。研究阿尔茨海默氏症的专家和 相关痴呆症(ADRD)和与选定的本科实习生(申请者： 接受度为7：1)，形成学员：指导二人组。ADRD和老化油田继续增长 然而，由URM科学家领导的实验室太少，新的URM培训人员也太少。FrA2RE是 导演：Gerald Schatten，博士(匹兹堡)，联合调查员Laura Niedernhofer，医学博士，博士， (明尼苏达州)，美国细胞生物学学会[ASCB]新配对主任乔治·兰福德博士 项目和研究经验协调员Calvin Simerly，博士，(PIT)组成高管 委员会审议阶段。由科学顾问委员会(SAB)监督，该委员会由温斯顿·汤普森博士、 (莫尔豪斯医学院：MSM)和梅丽莎·沃尔斯博士(JHU-Duluth土著教授)，他们 确保下一代本科生在职业选择上取得成功。FrA2RE开始 与Co-I George Langford在MBL的搭档在一个介绍性的周末，与George Langford的搭档 (10月)。然后，在≥一年的结构化研究经验之后，每年的队列完成该计划 在NIA年度ADAR峰会-GSA大会(11月)上举行了一次团聚。FrA2R毕业生， 在ADRD和老龄化研究职业生涯中，自我认同为34%的AA/B；38%的西班牙裔美国人；71%的人 女性，48%来自URM机构。FrA2RE预计会有许多来自部落国家的新兵。五个目标 建议：1.赞助有意义的结构化研究体验。二、确保多样性、公平性、 包含性和可访问性(DEIA)表示。三.通过培训来揭开监督要求的神秘面纱 负责任的研究行为(RCR)。提供职业规划和选择，特别是 他们加入了NIA-NIH的研究队伍；以及V.评估、改进和监测FrA2RE的优势 并通过不偏不倚、量化、独立的机制避免弱点。因此，FrA2RE将继续 加强和扩大最有前途的科学家的研究生涯，同时确保他们的研究 遵守美国国立卫生研究院的政策，将女性、少数群体和个人纳入整个生命周期，尤其是 NIA的重点是改善老年人和患有癌症的人的诊断、健康和福祉 阿尔茨海默氏症和相关疾病及其照顾者，以及生物学，临床，行为， 在社会、社会和老龄化方面，以及帮助纠正不平等现象和增加多样性。

PROJECT SUMMARY This renewal of R25 AG043365-10 for NIA’s “Advancing Diversity in Aging Research through Undergraduate Education (ADAR)” program, now re-entitled: “Frontiers in Alzheimer’s and Aging Research EXPERIENCES” (FrA2RE), requests support for five cohorts of ≥12 promising undergraduates annually who “…are eligible…if they are from economically, socially, culturally, or educationally disadvantaged backgrounds’ (responsive to PAR-20-317). FrA2RE concentrates on Structured Research Experiences and essential mentoring to launch and sustain careers within NIA’s portfolio. Experts investigating Alzheimer’s disease and Related Dementias (ADRD) and Aging partner with selected undergraduate trainees (applicants: acceptances is 7¼ :1), forming Trainee: Mentoring Dyads. The ADRD and aging fields continue to grow swiftly, yet there are too few laboratories led by URM scientists and too few new URM trainees. FrA2RE is directed by Gerald Schatten, PhD (Pittsburgh), with Co-Investigators Laura Niedernhofer, MD, PhD, (Minnesota), George Langford, PhD, Director of the American Society for Cell Biology’s [ASCB] new Pair-Up program, and Research Experiences Coordinator Calvin Simerly, PhD, (Pitt) forming the Executive Committee. Overseen by the Scientific Advisory Board (SAB), co-chaired by Winston Thompson, PhD, (Morehouse School of Medicine: MSM) and Melissa Walls, PhD (Indigenous Professor at JHU-Duluth), they ensure that the next generation of undergraduate trainees succeeds in their career choices. FrA2RE begins with an introductory ‘Meet and Greet’ weekend, partnering with Co-I George Langford’s Pair-Up at the MBL (Octobers). Then after ≥ year of structured research experiences, each year’s cohort completes the program with a Reunion held at the annual NIA’s ADAR summit-GSA congress (Novembers). FrA2R graduates, progressing in ADRD and aging-research careers, self-identify as 34% AA/B; 38% as Hispanic American; 71% are women, 48% are from URM institutions. FrA2RE anticipates many recruits from Tribal Nations. Five aims are proposed: I. Sponsor meaningful Structured Research Experiences. II. Ensure Diversity, Equity, Inclusion, and Accessibility (DEIA) representation. III. Demystify oversight requirements by training in responsible conduct of research (RCR). IV. Provide career planning and choices, particularly the possibility of them joining the NIA-NIH’s research workforce; and V. Evaluate, improve, and monitor FrA2RE’s strengths and avoid weaknesses with unbiased, quantitative, independent mechanisms. Thus, FrA2RE will continue to enhance and expand the research careers of the most promising scientists, while ensuring their investigations comply with NIH’s policy of ‘Inclusion of Women, Minorities, and Individuals Across the Lifespan,’ particularly NIA’s focus on improving the diagnoses, health, and well-being, among the elderly and those suffering from Alzheimer’s Dementia and Related Disorders and their caregivers, and biological, clinical, behavioral, social, aspects of aging, as well as helping to rectify inequities and increasing diversity.