Advanced MR Imaging of Early Osteoarthritis

早期骨关节炎的先进 MR 成像

基本信息

批准号：
8641320
负责人：
Garry E Gold
金额：
$ 15.53万
依托单位：
STANFORD UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-04-01 至 2017-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8641320
关键词：
Affect Area Award Biological Markers Biomechanics Biomedical Engineering Bone Marrow Cartilage Cartilage Matrix Clinical Collaborations Collagen Collection Cross-Sectional Studies Data Degenerative polyarthritis Detection Development Diffusion Discipline Disease Disease Progression Doctor of Philosophy Early Diagnosis Engineering Free Will Functional disorder Funding Glycosaminoglycans Gold Human Human Resources Image Imaging Device Individual Lead Learning Lesion Letters Longitudinal Studies Magnetic Resonance Imaging Maps Measures Mechanics Medical Students Meniscus structure of joint Mentors Methods Metric Mid-Career Clinical Scientist Award (K24)Midcareer Investigator Award in Patient-Oriented Research Musculoskeletal Musculoskeletal Diseases National Institute of Biomedical Imaging and Bioengineering Orthopedics Osteoarthrosis Deformans Patients Physicians Population Postdoctoral Fellow Protocols documentation Radiology Specialty Recording of previous events Relative (related person)Relaxation Request for Applications Research Research Personnel Resolution Resources Rheumatology Scanning Scientist Societies Sodium Staging Students Synovitis Techniques Technology Testing Thick Three-Dimensional Imaging Time Training United States National Institutes of Health Universities Wages Weight Work arthropathies career design effusion graduate student imaging modality improved in vivo insight musculoskeletal imaging novel novel strategies patient oriented research professor therapy development

项目摘要

DESCRIPTION (provided by applicant): This is a new application for a Midcareer Investigator Award in Patient-Oriented Research (K24). The applicant, Dr. Garry Gold, is a physician-scientist, Associate Professor of Radiology, Bioengineering, and Orthopedics at Stanford University. Over the past 10 years, Dr. Gold has developed expertise in several advanced musculoskeletal imaging and biomechanics techniques and applied these to the study of osteoarthritis and joint diseases. This has led to his developing an independent patient- oriented research (POR) career. He has received two independent research awards from the NIH that use MR techniques to investigate the pathophysiology of musculoskeletal diseases (both are from NIBIB). Dr. Gold has a 10-year history of mentoring junior clinician scientists, postdoctoral fellows, medical students, graduate students, and undergraduates - all performing POR. In addition, Dr. Gold has active collaborations with many NIH-funded investigators in the area of musculoskeletal research and imaging. The current application requests funding (40% salary) for 5 years. This funding will guarantee that the candidate will have at least 50% protected time to conduct his ongoing research and to continue to mentor clinician scientists performing POR. This award will free time now devoted to administrative and clinical responsibilities to focus more on his research and mentoring activities over the next 5 years. In addition to working on the two ongoing NIH-funded projects, Dr. Gold will obtain additional training in advanced MR collection and analysis methods. This will allow the candidate to develop new approaches to apply to the imaging of musculoskeletal diseases. Given the outstanding resources and collaborations at Stanford, these novel projects are expected to be either renewed or to lead to new directions in orthopedic research, and significantly contribute to our scientific understanding of these disabling conditions.

描述（由申请人提供）：这是针对患者研究的中级护理研究者奖（K24）的新申请。申请人Garry Gold博士是斯坦福大学的医师科学家，放射学，生物工程和骨科副教授。在过去的10年中，Gold博士在几种晚期肌肉骨骼成像和生物力学技术方面发展了专业知识，并将其应用于骨关节炎和关节疾病的研究。这导致他发展了独立的面向患者的研究（POR）职业。他获得了NIH的两个独立研究奖，他们使用MR技术研究了肌肉骨骼疾病的病理生理学（两者均来自Nibib）。 Gold博士有10年的历史，指导初级临床医生，博士后研究员，医学生，研究生和本科生 - 都表现出色。此外，Gold博士与许多NIH资助的研究人员在肌肉骨骼研究和成像领域进行了积极的合作。当前的申请要求提供5年的资金（40％的薪水）。这笔资金将确保候选人至少有50％的保护时间来进行他正在进行的研究，并继续指导临床医生进行POR。该奖项现在将献身于行政和临床职责，以便在未来5年内更多地专注于他的研究和指导活动。除了从事两个正在进行的NIH资助的项目外，Gold博士还将在高级MR收集和分析方法中获得其他培训。这将使候选人能够开发出新方法，以应用于肌肉骨骼疾病的成像。鉴于斯坦福大学的出色资源和合作，预计这些新型项目将被续签或导致骨科研究的新方向，并为我们的科学理解做出重大贡献这些禁用条件。