The Essential Nuclear Transporter Importin 13; key role in brain and testis
The Essential Nuclear Transporter Importin 13; key role in brain and testis
批准号:
nhmrc : 1022206
负责人:
Prof David Jans
金额:
$40.88万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
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英文摘要
Transport into and out of the nucleus, the control centre of cells, is critical for cell function in complex organisms such as mammals. The present proposal seeks to further understanding of a novel molecule mediating nuclear transport that has a novel inhibitory form in the testis, and important roles in the lung and nervous system. The results should help basic understanding of this molecule, and relate to disease conditions such as X-linked mental retardation and childhood asthma.
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