Nuclear Transport in Health and Disease; Towards Therapeutics
Nuclear Transport in Health and Disease; Towards Therapeutics
批准号:
nhmrc : GNT1103050
负责人:
Prof David Jans
金额:
$85.2万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
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英文摘要
This research fellowship will enable new therapeutic approaches to viral disease and cancer that target the transport process. I have already licenced an inhibitory molecule for Dengue virus which is progressing towards the clinic. I will now extend my research into a vibrant translational program of developing anti-viral (HIV, Respiratory Syncytical Virus, VEEV) as well as anti-cancer agents that will represent realistic therapeutic options in the near future.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Nuclear transport in stress
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批准号:DP190101966
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项目类别:Discovery Projects
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资助金额:$37.21万
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财政年份:2019
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负责人:Prof David Jans
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依托单位:
Epigenetic regulation by PKC-theta in human breast cancer stem cells.
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批准号:nhmrc : GNT1105409
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项目类别:Project Grants
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资助金额:$81.81万
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财政年份:2016
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负责人:Prof David Jans
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依托单位:
Nuclear Transport in Health and Disease; Towards Therapeutics
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批准号:nhmrc : 1103050
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项目类别:Research Fellowships
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资助金额:$58.74万
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财政年份:2016
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负责人:Prof David Jans
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依托单位:
Epigenetic regulation by PKC-theta in human breast cancer stem cells.
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批准号:nhmrc : 1105409
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项目类别:Project Grants
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资助金额:$56.28万
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财政年份:2016
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负责人:Prof David Jans
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依托单位:
Transcription factor nuclear residency as a driver of gene expression
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批准号:DP130100804
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项目类别:Discovery Projects
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资助金额:$25.6万
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财政年份:2013
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负责人:Prof David Jans
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依托单位:
Respiratory Syncytial Virus Matrix Protein-Host Protein Interactions as Targets for Therapeutics
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批准号:nhmrc : 1043511
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项目类别:Project Grants
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资助金额:$45.8万
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财政年份:2013
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负责人:Prof David Jans
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依托单位:
The Essential Nuclear Transporter Importin 13; key role in brain and testis
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批准号:nhmrc : 1022206
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项目类别:Project Grants
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资助金额:$40.88万
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财政年份:2012
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负责人:Prof David Jans
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依托单位:
Rhinovirus protease subcellular trafficking and host cell targets; relevance to asthma exacerbation and vaccine approaches
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批准号:nhmrc : 1027312
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项目类别:Project Grants
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资助金额:$38.81万
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财政年份:2012
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负责人:Prof David Jans
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依托单位:
Enhanced nuclear transport in transformed cells; implications for cancer treatment
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批准号:nhmrc : 1032143
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项目类别:Project Grants
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资助金额:$41.92万
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财政年份:2012
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负责人:Prof David Jans
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依托单位:
Regulation of nucleocytoplasmic transport; role in health and disease
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批准号:nhmrc : 1002486
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项目类别:Research Fellowships
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资助金额:$54.88万
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财政年份:2011
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负责人:Prof David Jans
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依托单位:
New targets for antiviral therapies
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批准号:DP110101749
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项目类别:Discovery Projects
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资助金额:$29.56万
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财政年份:2011
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负责人:Prof David Jans
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依托单位:
Regulation of subcellular localisation of respiratory syncytial virus M protein: implications for pathology
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批准号:nhmrc : 606407
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项目类别:NHMRC Project Grants
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资助金额:$38.69万
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财政年份:2010
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负责人:Prof David Jans
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依托单位:
Nuclear functions of Dengue NS5 protein: role in disease
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批准号:nhmrc : 606409
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项目类别:NHMRC Project Grants
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资助金额:$49.14万
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财政年份:2010
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负责人:Prof David Jans
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依托单位:
Novel microtubule association sequences from rabies virus; subversion of antiviral responses and use in drug delivery
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批准号:nhmrc : 545838
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项目类别:NHMRC Project Grants
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资助金额:$35.32万
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财政年份:2009
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负责人:Prof David Jans
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依托单位:
Negative regulators of nuclear import; potential links to cancer
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批准号:nhmrc : 491055
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项目类别:NHMRC Project Grants
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资助金额:$33.06万
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财政年份:2008
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负责人:Prof David Jans
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依托单位:
Role of nucleocytoplasmic trafficking of Matrix protein in RSV infection
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批准号:nhmrc : 436611
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项目类别:NHMRC Project Grants
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资助金额:$33.01万
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财政年份:2007
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负责人:Prof David Jans
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依托单位:
The tumour cell-specific nuclear targeting properties of chicken anaemia virus VP-3: potential for anti-tumour therapy
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批准号:nhmrc : 436614
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项目类别:NHMRC Project Grants
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资助金额:$31.02万
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财政年份:2007
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负责人:Prof David Jans
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依托单位:
Role of the microtubule network in nuclear transport: potential use in gene delivery
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批准号:nhmrc : 384107
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项目类别:NHMRC Project Grants
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资助金额:$32.79万
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财政年份:2006
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负责人:Prof David Jans
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依托单位:
Research Fellowship - Grant ID:384105
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批准号:nhmrc : 384105
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项目类别:NHMRC Research Fellowships
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资助金额:$50.09万
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财政年份:2006
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负责人:Prof David Jans
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依托单位:
Engineered histones as DNA carriers with application in therapeutic gene delivery
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批准号:nhmrc : 284205
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项目类别:NHMRC Project Grants
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资助金额:$27.86万
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财政年份:2004
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负责人:Prof David Jans
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依托单位:
国内基金
海外基金
Toward a general theory of intermittent aeolian and fluvial nonsuspended sediment transport
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批准号:--
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项目类别:--
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资助金额:55万元
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批准年份:2022
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负责人:Thomas Pahtz
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依托单位:
Intraflagellar Transport运输纤毛蛋白的分子机理
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批准号:31371354
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项目类别:面上项目
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资助金额:90.0万元
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批准年份:2013
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负责人:黄开耀
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依托单位:
苜蓿根瘤菌(S.meliloti)四碳二羧酸转运系统 (Dicarboxylate transport system, Dct系统)跨膜信号转导机理
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批准号:30870030
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项目类别:面上项目
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资助金额:30.0万元
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批准年份:2008
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负责人:文津
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依托单位: