Regulation of nucleocytoplasmic transport; role in health and disease
Regulation of nucleocytoplasmic transport; role in health and disease
批准号:
nhmrc : 1002486
负责人:
Prof David Jans
金额:
$54.88万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2016-12-31
中文摘要
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英文摘要
Transport into and out of the nucleus is central to the function of the cells from complex organisms such as mammals. This research program aims to improve understanding of nuclear transport and its regulation in the context of infection by medically relevant viruses, as well as in the context of cancer, and normal cell growth/development. It will contribute to developing new anti-viral therapeutics/vaccines, drug delivery strategies for cancer, and understanding causes of male infertility.
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会议论文
Nuclear transport in stress
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批准号:DP190101966
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项目类别:Discovery Projects
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资助金额:$37.21万
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财政年份:2019
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负责人:Prof David Jans
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依托单位:
Nuclear Transport in Health and Disease; Towards Therapeutics
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批准号:nhmrc : GNT1103050
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项目类别:Research Fellowships
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资助金额:$85.2万
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财政年份:2016
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负责人:Prof David Jans
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依托单位:
Epigenetic regulation by PKC-theta in human breast cancer stem cells.
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批准号:nhmrc : GNT1105409
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项目类别:Project Grants
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资助金额:$81.81万
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财政年份:2016
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负责人:Prof David Jans
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依托单位:
Nuclear Transport in Health and Disease; Towards Therapeutics
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批准号:nhmrc : 1103050
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项目类别:Research Fellowships
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资助金额:$58.74万
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财政年份:2016
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负责人:Prof David Jans
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依托单位:
Epigenetic regulation by PKC-theta in human breast cancer stem cells.
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批准号:nhmrc : 1105409
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项目类别:Project Grants
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资助金额:$56.28万
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财政年份:2016
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负责人:Prof David Jans
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依托单位:
Transcription factor nuclear residency as a driver of gene expression
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批准号:DP130100804
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项目类别:Discovery Projects
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资助金额:$25.6万
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财政年份:2013
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负责人:Prof David Jans
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依托单位:
Respiratory Syncytial Virus Matrix Protein-Host Protein Interactions as Targets for Therapeutics
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批准号:nhmrc : 1043511
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项目类别:Project Grants
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资助金额:$45.8万
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财政年份:2013
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负责人:Prof David Jans
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依托单位:
The Essential Nuclear Transporter Importin 13; key role in brain and testis
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批准号:nhmrc : 1022206
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项目类别:Project Grants
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资助金额:$40.88万
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财政年份:2012
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负责人:Prof David Jans
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依托单位:
Rhinovirus protease subcellular trafficking and host cell targets; relevance to asthma exacerbation and vaccine approaches
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批准号:nhmrc : 1027312
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项目类别:Project Grants
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资助金额:$38.81万
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财政年份:2012
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负责人:Prof David Jans
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依托单位:
Enhanced nuclear transport in transformed cells; implications for cancer treatment
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批准号:nhmrc : 1032143
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项目类别:Project Grants
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资助金额:$41.92万
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财政年份:2012
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负责人:Prof David Jans
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依托单位:
New targets for antiviral therapies
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批准号:DP110101749
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项目类别:Discovery Projects
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资助金额:$29.56万
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财政年份:2011
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负责人:Prof David Jans
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依托单位:
Regulation of subcellular localisation of respiratory syncytial virus M protein: implications for pathology
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批准号:nhmrc : 606407
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项目类别:NHMRC Project Grants
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资助金额:$38.69万
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财政年份:2010
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负责人:Prof David Jans
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依托单位:
Nuclear functions of Dengue NS5 protein: role in disease
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批准号:nhmrc : 606409
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项目类别:NHMRC Project Grants
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资助金额:$49.14万
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财政年份:2010
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负责人:Prof David Jans
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依托单位:
Novel microtubule association sequences from rabies virus; subversion of antiviral responses and use in drug delivery
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批准号:nhmrc : 545838
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项目类别:NHMRC Project Grants
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资助金额:$35.32万
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财政年份:2009
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负责人:Prof David Jans
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依托单位:
Negative regulators of nuclear import; potential links to cancer
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批准号:nhmrc : 491055
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项目类别:NHMRC Project Grants
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资助金额:$33.06万
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财政年份:2008
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负责人:Prof David Jans
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依托单位:
Role of nucleocytoplasmic trafficking of Matrix protein in RSV infection
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批准号:nhmrc : 436611
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项目类别:NHMRC Project Grants
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资助金额:$33.01万
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财政年份:2007
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负责人:Prof David Jans
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依托单位:
The tumour cell-specific nuclear targeting properties of chicken anaemia virus VP-3: potential for anti-tumour therapy
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批准号:nhmrc : 436614
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项目类别:NHMRC Project Grants
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资助金额:$31.02万
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财政年份:2007
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负责人:Prof David Jans
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依托单位:
Role of the microtubule network in nuclear transport: potential use in gene delivery
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批准号:nhmrc : 384107
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项目类别:NHMRC Project Grants
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资助金额:$32.79万
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财政年份:2006
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负责人:Prof David Jans
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依托单位:
Research Fellowship - Grant ID:384105
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批准号:nhmrc : 384105
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项目类别:NHMRC Research Fellowships
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资助金额:$50.09万
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财政年份:2006
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负责人:Prof David Jans
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依托单位:
Engineered histones as DNA carriers with application in therapeutic gene delivery
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批准号:nhmrc : 284205
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项目类别:NHMRC Project Grants
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资助金额:$27.86万
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财政年份:2004
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负责人:Prof David Jans
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依托单位:
国内基金
海外基金
核孔蛋白NUP62调控开花时间的分子机制
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批准号:31970730
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项目类别:面上项目
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资助金额:58.0万元
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批准年份:2019
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负责人:胡红红
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依托单位: