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Engineering enzymes for natural product glycodiversification

Engineering enzymes for natural product glycodiversification
用于天然产物糖多样化的工程酶
批准号:
249801-2009
负责人:
Jakeman, David
金额:
$4.37万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-01-01 至 2011-12-31

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中文摘要
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英文摘要
Our bioorganic chemistry program has the broad goals of furthering an understanding of the physiological roles played by carbohydrate-manipulating enzymes and using these catalysts to perform novel chemistry. The proposed research will use: synthetic chemistry to access novel substrates; mutagenesis and kinetic analyses to probe and evolve catalyst function; and NMR spectroscopy to provide structural insight into protein-ligand interactions.
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Carbohydrates, enzymes and natural products
  • 批准号:
    RGPIN-2020-03893
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.62万
  • 财政年份:
    2022
  • 负责人:
    Jakeman, David
  • 依托单位:
Carbohydrates, enzymes and natural products
  • 批准号:
    RGPIN-2020-03893
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.62万
  • 财政年份:
    2021
  • 负责人:
    Jakeman, David
  • 依托单位:
Carbohydrates, enzymes and natural products
  • 批准号:
    RGPIN-2020-03893
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.62万
  • 财政年份:
    2020
  • 负责人:
    Jakeman, David
  • 依托单位:
To inform drug design for COVID-19: Computational determination of interactions between COVID-19 gene products and structurally diverse natural products and clinical drugs
  • 批准号:
    550135-2020
  • 项目类别:
    Alliance Grants
  • 资助金额:
    $3.64万
  • 财政年份:
    2020
  • 负责人:
    Jakeman, David
  • 依托单位:
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