Engineering enzymes for natural product glycodiversification
Engineering enzymes for natural product glycodiversification
批准号:
249801-2009
负责人:
Jakeman, David
金额:
$4.37万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31
中文摘要
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英文摘要
Our bioorganic chemistry program has the broad goals of furthering an understanding of the physiological roles played by carbohydrate-manipulating enzymes and using these catalysts to perform novel chemistry. The proposed research will use: synthetic chemistry to access novel substrates; mutagenesis and kinetic analyses to probe and evolve catalyst function; and NMR spectroscopy to provide structural insight into protein-ligand interactions.
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会议论文
Carbohydrates, enzymes and natural products
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批准号:RGPIN-2020-03893
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.62万
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财政年份:2022
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负责人:Jakeman, David
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依托单位:
Carbohydrates, enzymes and natural products
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批准号:RGPIN-2020-03893
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.62万
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财政年份:2021
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负责人:Jakeman, David
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依托单位:
Carbohydrates, enzymes and natural products
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批准号:RGPIN-2020-03893
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.62万
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财政年份:2020
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负责人:Jakeman, David
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依托单位:
To inform drug design for COVID-19: Computational determination of interactions between COVID-19 gene products and structurally diverse natural products and clinical drugs
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批准号:550135-2020
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项目类别:Alliance Grants
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资助金额:$3.64万
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财政年份:2020
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负责人:Jakeman, David
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依托单位:
Carbohydrates, enzymes and natural products
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批准号:RGPIN-2015-03876
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2019
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负责人:Jakeman, David
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依托单位:
Carbohydrates, enzymes and natural products
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批准号:RGPIN-2015-03876
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2018
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负责人:Jakeman, David
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依托单位:
Carbohydrates, enzymes and natural products
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批准号:RGPIN-2015-03876
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2017
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负责人:Jakeman, David
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依托单位:
Chemoenzymatic methods to prepare N-glucuronides for use in drug discovery
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批准号:492417-2015
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项目类别:Engage Grants Program
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资助金额:$1.82万
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财政年份:2016
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负责人:Jakeman, David
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依托单位:
Carbohydrates, enzymes and natural products
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批准号:RGPIN-2015-03876
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
-
财政年份:2016
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负责人:Jakeman, David
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依托单位:
Carbohydrates, enzymes and natural products
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批准号:RGPIN-2015-03876
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2015
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负责人:Jakeman, David
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依托单位:
Engineering enzymes for natural product glycodiversification
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批准号:249801-2009
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.37万
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财政年份:2014
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负责人:Jakeman, David
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依托单位:
Structural, enzymatic and cellular mechanism of action studies on new jadomycins
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批准号:385830-2010
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项目类别:Collaborative Health Research Projects
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资助金额:$5.77万
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财政年份:2012
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负责人:Jakeman, David
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依托单位:
Engineering enzymes for natural product glycodiversification
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批准号:249801-2009
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项目类别:Discovery Grants Program - Individual
-
资助金额:$4.37万
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财政年份:2012
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负责人:Jakeman, David
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依托单位:
A SmartPROBE for NMR studies
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批准号:422168-2012
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$10.93万
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财政年份:2011
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负责人:Jakeman, David
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依托单位:
Structural, enzymatic and cellular mechanism of action studies on new jadomycins
-
批准号:385830-2010
-
项目类别:Collaborative Health Research Projects
-
资助金额:$5.77万
-
财政年份:2011
-
负责人:Jakeman, David
-
依托单位:
Structural, enzymatic and cellular mechanism of action studies on new jadomycins
-
批准号:385830-2010
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项目类别:Collaborative Health Research Projects
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资助金额:$6.06万
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财政年份:2010
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负责人:Jakeman, David
-
依托单位:
Engineering enzymes for natural product glycodiversification
-
批准号:249801-2009
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$4.37万
-
财政年份:2010
-
负责人:Jakeman, David
-
依托单位:
Engineering enzymes for natural product glycodiversification
-
批准号:249801-2009
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$4.37万
-
财政年份:2009
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负责人:Jakeman, David
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依托单位:
NSERC CREATE networking CB2TOP opportunities
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批准号:371991-2008
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项目类别:Regional Office Discretionary Funds - Atlantic
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资助金额:$0.33万
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财政年份:2008
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负责人:Jakeman, David
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依托单位:
Biological Chemistry
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批准号:249801-2006
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.46万
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财政年份:2008
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负责人:Jakeman, David
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依托单位:
海外基金