Development and optimization of an automated platform for the formulation of polymeric nanoparticles

聚合物纳米粒子配方自动化平台的开发和优化

• 批准号: 485890-2015
• 负责人: Banquy, Xavier
• 金额: $ 1.79万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=585258
• 关键词: Development; optimization; automated; platform; formulation

This project is focused on the development of new fabrication techniques for the production of medicated nanoparticles based on polymeric binders. The method makes use of microfluidic micro mixing in order to obtain particle with a nominal size in the nanometer range and low polydispersity. Different types of micromixers will be tested in order to identify the best candidate for a given family of molecular binder. This research will allow the industrial partner with design knowledge for futur implementation of the micromixer into their currently available products.

该项目致力于开发用于药物生产的新的制造技术。 基于聚合物粘结剂的纳米颗粒。该方法利用微流控微混合，以 获得标称尺寸在纳米范围、低多分散性的颗粒。不同类型的 将对微型混合器进行测试，以确定特定分子粘结剂家族的最佳候选者。这 研究将使工业合作伙伴拥有未来实施微型混合器的设计知识 转化为他们目前可用的产品。