Novel, Low-Cost COVID-19 Point of Care Monitoring and Triaging Device

新型、低成本的 COVID-19 护理点监测和分诊设备

• 批准号: 553917-2020
• 负责人: Mowat, Vicki
• 金额: $ 5.46万
• 依托单位: Sheridan Institute of Technology and Advanced Learning
• 依托单位国家: 加拿大
• 项目类别: Applied Research Rapid Response to COVID-19
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=695380
• 关键词: Novel; Low; Cost; COVID; 19

Testing for COVID-19 is a major strategy to manage the pandemic and one of the most important criteria and measures that are needed to restart the economy in Canada (First Ministers' statement on shared public health approach to support restarting the economy, April 28, 2020). Two types of diagnostic devices are commonly used: 1) Lab-based devices and 2) Point of Care (PoC) devices, which are mobile solutions that can be used at homes, in doctors' offices and long-term care homes. Only one nucleic acid-based PoC device is authorized by Health Canada to date. While this device focuses on COVID-19 diagnosis, there are still no mobile health-based (mHealth-based) tools that are inexpensive and can be used to collect real-time vital signs related to COVID-19. These signs are important for early assessment and monitoring of potential cases (people in self-isolation), false-negative cases (cases that test negative but require further monitoring), or groups at risks such as elderly people living in long-term care homes. To support these important demands, our goal is to mobilize a simple, accessible and cost-effective PoC COVID-19 self-assessment and monitoring system. This goal will be achieved by rapidly reconfiguring our existing mHealth-based PoC system, called NewPneu, which was designed to assist in pneumonia assessment in children. The reconfigured system will support more effective, efficient and real-time monitoring of people of all ages who test positive for COVID-19. The new system will also support triaging of potential cases of COVID-19 that need hospital referral for further management and diagnosis (i.e., nucleic acid-based testing).

新冠肺炎检测是控制疫情的一项重要战略，也是重振加拿大经济所需的最重要的标准和措施之一(2020年4月28日，第一部长关于共同公共卫生方法以支持重启经济的声明)。通常使用两种类型的诊断设备：1)基于实验室的设备和2)护理点(PoC)设备，这是一种可在家庭、医生办公室和长期护理之家使用的移动解决方案。到目前为止，加拿大卫生部只批准了一种基于核酸的PoC设备。 虽然这款设备专注于新冠肺炎诊断，但目前还没有基于移动健康的(基于移动健康的)工具，这些工具价格低廉，可以用来收集与新冠肺炎相关的实时生命体征。这些迹象对于早期评估和监测潜在病例(处于自我隔离状态的人)、假阴性病例(检测呈阴性但需要进一步监测的病例)或高危群体，如居住在长期护理院的老年人非常重要。 为了支持这些重要需求，我们的目标是动员一个简单、可访问和高性价比的PoC新冠肺炎自我评估和监测系统。这一目标将通过快速重新配置我们现有的基于mHealth的PoC系统NewPneu来实现，该系统旨在帮助评估儿童肺炎。重新配置的系统将支持对新冠肺炎检测呈阳性的各个年龄段的人进行更有效、更高效和更实时的监测。新系统还将支持对需要医院转诊进行进一步管理和诊断(即基于核酸的检测)的新冠肺炎潜在病例进行分流。