Bioreactor Development for the Induction, Proliferation, andUse of Structurally Differentiated Plant Tissue Culture for Secondary Metabolite Production

这项建议旨在测试是否可以通过以下方式增加次生代谢物的产量：-了解固定化对植物细胞生化和结构分化的影响，以及-研究用于生长和有效利用器官组织生产次生代谢物的反应器设计和操作。本项目的结果表明，固定化可以导致生化和结构分化的显着增加。PI计划测试质量传递梯度、细胞基质相互作用和细胞联合在此类反应中所起的作用。

This proposal seeks to test whether secondary metabolite production can be increased through: - the development of an understanding of the effects of immobilization on biochemical and structural differentiation in plant cells, and - the study of reactor design and operation for the growth and the effective use of organ tissues for the production of secondary metabolites. Results from the current project suggest that immobilization can result in a significant increase in biochemical and structural differentiation. The PIs plan to test the role that mass transfer gradients, cell matrix interactions, and cellular association play in such responses.