Acquisition of a 500 MHz NMR Spectrometer

核磁共振（NMR）光谱是最 化学家可以用来阐明 分子的结构 它用于识别未知 物质，表征内部原子的特定排列 分子，并研究相互作用的动力学之间 溶液中的分子。 获得最先进的NMR 光谱学对化学家和生物学家来说是必不可少的， 开展前沿研究。 纽约州立大学斯托尼布鲁克分校的化学系将使用 该奖项由化学仪器计划和 仪器和仪表开发计划，以帮助 获取一台高场核磁共振光谱仪 化学领域 和生物学研究， 收购包括： 1)生理活性物质的合成和生物化学 脂质、多肽和碳水化合物 2)基于胆汁酸的分子受体 3)化合物活性中心的合成类似物的NMR研究 金属蛋白和多相金属硫化物催化剂 4)位点特异性酶与DNA修饰 5)杂环合成与分子识别。

Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to the chemist for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectroscopy is essential to chemists and biologists who are carrying out frontier research. The Department of Chemistry of SUNY at Stony Brook will use this award from the Chemical Instrumentation Program and the Instrumentation and Instrument Development Program to help acquire a high-field NMR spectrometer. The areas of chemical and biological research that will be enhanced by the acquisition include: 1) Synthetic and biological chemistry of physiologically-active lipids, polypeptides and carbohydrates 2) Molecular receptors based on bile acids 3) NMR studies of synthetic anologs for the active sites of metalloproteins and heterogeneous metal-sulfide catalysts 4) Site-specific enzyme and DNA modification 5) Heterocyclic synthesis and molecular recognition.