Regulation of lipolysis: new players, new paradigms
Regulation of lipolysis: new players, new paradigms
批准号:
DP0986389
负责人:
Prof Matthew Watt
金额:
$24.6万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2011-12-31
中文摘要
人们对脂肪分解的方式知之甚少。这项研究将确定脂肪分解过程中蛋白质的开启和关闭有多重要。通过了解这种关系,将开发出有效的药物治疗方法,增强燃烧脂肪的能力,最终减少2型糖尿病和心血管疾病的发病率,并减轻社区和医疗保健系统的相关经济负担。了解脂肪分解对于开发食品工业中的新加工技术也很重要。
英文摘要
The way in which fat is broken down is poorly understood. This research will determine how important proteins in fat breakdown are turned on and off. By understanding this relationship, effective pharmaceutical treatments will be developed that will enhance the capacity to burn fat and ultimately reduce the incidence of type 2 diabetes and cardiovascular disease, and ease the associated financial burden on the community and healthcare system. Understanding fat breakdown is also important for developing new processing technologies in the food industry.
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依托单位:
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依托单位:
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批准号:nhmrc : GNT1077703
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项目类别:Research Fellowships
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资助金额:$61.16万
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财政年份:2015
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财政年份:2015
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依托单位:
Altered protein secretion links the fatty liver to metabolic disease
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批准号:nhmrc : 1061278
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项目类别:Project Grants
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资助金额:$27.73万
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财政年份:2014
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负责人:Prof Matthew Watt
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依托单位:
Curing fatty muscles: understanding the role of PLIN5 in lipid metabolism and tissue function
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批准号:nhmrc : 1047138
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项目类别:Project Grants
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资助金额:$30.82万
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财政年份:2013
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负责人:Prof Matthew Watt
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依托单位:
Identifying a novel role for pigment epithelium-derived factor in obesity-related metabolic dysfunction
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批准号:nhmrc : 606561
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财政年份:2010
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负责人:Prof Matthew Watt
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依托单位:
Regulation of insulin sensitivity by reactive oxygen species
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批准号:nhmrc : 606604
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项目类别:NHMRC Project Grants
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资助金额:$37.65万
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财政年份:2010
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负责人:Prof Matthew Watt
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 606460
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项目类别:NHMRC Research Fellowships
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资助金额:$39.41万
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财政年份:2010
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负责人:Prof Matthew Watt
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依托单位:
Circulating ceramides, inflammation and insulin resistance
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批准号:nhmrc : 546027
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项目类别:NHMRC Project Grants
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资助金额:$23.89万
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财政年份:2009
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负责人:Prof Matthew Watt
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依托单位:
Adipose triglyceride lipase: regulation and implications for the aetiology of insulin resistance
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资助金额:$21.57万
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财政年份:2008
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负责人:Prof Matthew Watt
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依托单位:
Molecular and cell biology of lipid metabolism in chronic metabolic disease
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批准号:nhmrc : 448319
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项目类别:Career Development Fellowships
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资助金额:$21.69万
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财政年份:2007
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负责人:Prof Matthew Watt
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依托单位:
Molecular basis of skeletal muscle lipoapoptosis
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批准号:DP0663443
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资助金额:$17.9万
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财政年份:2006
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负责人:Prof Matthew Watt
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依托单位:
Cellular basis of cytokine-mediated fat metabolism and insulin resistance
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批准号:nhmrc : 292917
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项目类别:Early Career Fellowships
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资助金额:$14.44万
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财政年份:2004
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负责人:Prof Matthew Watt
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依托单位:
海外基金