Adipose triglyceride lipase: regulation and implications for the aetiology of insulin resistance
Adipose triglyceride lipase: regulation and implications for the aetiology of insulin resistance
批准号:
nhmrc : 502607
负责人:
Prof Matthew Watt
金额:
$21.57万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31
中文摘要
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英文摘要
Obese individuals have elevated fat levels in the blood and muscle, which contributes to the development of other diseases such as type 2 diabetes. A newly discovered protein named adipose triglyceride lipase (ATGL) is essential for fat breakdown. This project aims to identify how ATGL operates and determine whether defective ATGL function leads to type 2 diabetes. These studies will assist in the development of strategies aimed at reducing fatty acids in blood and muscle.
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批准号:nhmrc : GNT1077703
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财政年份:2015
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依托单位:
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批准号:nhmrc : 1077703
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资助金额:$42.58万
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财政年份:2015
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Altered protein secretion links the fatty liver to metabolic disease
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批准号:nhmrc : 1061278
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项目类别:Project Grants
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财政年份:2014
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依托单位:
Curing fatty muscles: understanding the role of PLIN5 in lipid metabolism and tissue function
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批准号:nhmrc : 1047138
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资助金额:$30.82万
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财政年份:2013
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负责人:Prof Matthew Watt
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依托单位:
Identifying a novel role for pigment epithelium-derived factor in obesity-related metabolic dysfunction
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资助金额:$24.11万
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财政年份:2010
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依托单位:
Regulation of insulin sensitivity by reactive oxygen species
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批准号:nhmrc : 606604
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依托单位:
Uncoupled Research Fellowship
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财政年份:2010
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负责人:Prof Matthew Watt
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依托单位:
Circulating ceramides, inflammation and insulin resistance
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财政年份:2009
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负责人:Prof Matthew Watt
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依托单位:
Regulation of lipolysis: new players, new paradigms
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资助金额:$24.6万
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财政年份:2009
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负责人:Prof Matthew Watt
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依托单位:
Molecular and cell biology of lipid metabolism in chronic metabolic disease
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财政年份:2007
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依托单位:
Molecular basis of skeletal muscle lipoapoptosis
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财政年份:2006
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负责人:Prof Matthew Watt
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依托单位:
Cellular basis of cytokine-mediated fat metabolism and insulin resistance
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负责人:Prof Matthew Watt
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依托单位:
国内基金
海外基金
二甲双胍对肥胖自发2型糖尿病大鼠脂肪分解变化规律的影响及机制
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批准号:81000347
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项目类别:青年科学基金项目
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资助金额:20.0万元
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批准年份:2010
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负责人:张婷婷
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依托单位: