Purchase of an X-ray Diffractometer

获得化学研究仪器和设施多用户计划（CRIF:MU）的这一奖项后，Marsha I. Lester教授将获得一台x射线衍射仪，供宾夕法尼亚大学化学系的许多用户以及邻近机构的一些研究人员使用。将从该奖项中受益的主要研究项目是在合成、催化和材料领域。例子包括nhc -碳烯催化反应、多肽合成、设计、高亲和力结合氙的有机笼的表征（用于生物成像）、不对称有机化合物和苝丙二酮天然产物的鉴定、聚硼烷化合物、不对称催化和机理研究。衍射仪还将用于K12学生和教师以及本科生和研究生的外展活动。x射线衍射仪可以精确测量分子的完整三维结构，包括键距和角度，并提供有关分子相对于邻近分子的空间排列的准确信息。这里描述的研究将影响许多领域，包括化学、材料化学和生物化学。该仪器将成为教学和研究的一个组成部分。

With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), Professor Marsha I. Lester will acquire an X-ray diffractometer to be used by many users in the Department of Chemistry at the University of Pennsylvania as well as by some researchers from neighboring institutions. The main research projects that will benefit from this award are in areas of synthesis, catalysis, and materials. Examples involve NHC-carbene catalyzed reactions, peptide synthesis, design, characterization of organic cages that bind xenon with high affinity which are useful for biological imaging, identification of asymmetric organic compounds and perylenequinone natural products, polyborane compounds, asymmetric catalysis, and mechanistic investigations. The diffractometer will also be used in outreach activities involving K12 students and teachers as well as undergraduate and graduate students.An X-ray diffractometer allows accurate and precise measurements of the full three dimensional structure of a molecule, including bond distances and angles, and provides accurate information about the spatial arrangement of a molecule relative to neighboring molecules. The studies described here will impact a number of areas, including chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research.