Fabrication of passive surface to protein by physicochemical proteomics approach

我们评价了多肽在表面的吸附行为。合成了具有不同氨基酸种类和比对的模型多肽。表面官能团由自组装单分子膜(SAM)控制。用表面等离子体共振法测量了它们的吸收行为。结果表明，具有疏水基团的多肽通过静电引力吸附到疏水表面，带电荷的多肽通过静电引力吸附到表面。

We evaluated absorption behaviors of peptides to the surfaces. The model peptides which have different kinds and alignments of amino acids were synthesized. The functional groups of surfaces were controlled by self-assemble monolayers(SAMs). The absorption behaviors were measured by surface plasmon resonance. From results, it was found that the peptide which has hydrophobic groups absorb to hydrophobic surface and the peptide which has charge absorbs to the surface by electrostatic attractive force.