Creation and Practical Use of Multipurpose Hybrid Fibers from Natural Polymeric Materials by Watery Interfacial

1.探索新型海洋黏附蛋白及其分子结构：首次对翡翠贻贝黏附蛋白进行了纯化。翡翠贻贝足部蛋白-1(Pvfp-1)是一种新的糖基化蛋白。其他蛋白质Pvfp-2、-3、-4、-5、-6、-7、-8也可作为体部前体蛋白，其中一些蛋白质可作为男性耐久耐久船舱的粘合剂。2.水法制备可光交联聚氨基酸S及其在杂化纤维中的应用：将两种阳离子多肽：聚(L赖氨酸)(PLL)和聚(L-鸟氨酸)(PLO)处理后，在PLL和PLO的侧链氨基上引入光活性的酰氧乙酰基团。将得到的含有香豆素的阳离子多肽与阴离子多糖结冷凝胶在水中纺制成PLC纤维。含香豆素的聚对苯二甲酸二异氰酸酯(…)纤维的机械强度进一步提高。水溶液界面自组装生物聚合物杂化胶囊的制备：真正的球形胶囊是壳聚糖和结冷胶在水溶液中通过多离子络合物(PIC)形成的静电多糖相互作用形成的。将壳聚糖溶液滴加到结冷胶溶液中，得到外表面为结冷胶、内层为壳聚糖的球形胶囊。用低分子物质和高分子蛋白质检测胶囊的释放性能。4.来自海洋贻贝生物合成系统的增强纤维材料：海洋贻贝生物合成系统涉及的分子机制启发了在水介质中创造杂化材料的新技术。在我们创造仿生杂化纤维、胶囊、水凝胶和粘合剂的一系列研究中，我们专注于苯醌偶联化学，它伴随着体节的形成而发生。设计合成了新型多糖类和多(氨基酸)类化合物。它们将接枝的肽侧CHAP作为酶介导的交联剂，允许对杂化材料进行机械增强。较少

1.Exploring New Marine Adhesive Protein and its Molecular Structure : The adhesive protein of the green mussel Perna viridis was firstly purified. The molecular structure of the Perna viridis foot protein-1 (Pvfp-1) was characterized as a novel glycosylated protein. The other proteins, Pvfp-2, -3, -4, -5, -6, -7, -and -8 were also found as the byssus precursor protein, and some of them functions as the adhesives to male durable marine holdfast.2.Synthesis of photo-crosslinkable poly(amino acid)s by watery process and its application for hybrid fibers : Two kinds of cationic polypeptides, poly(L-lysine) (PLL) and poly(L-ornithine) (PLO) were treated to incorporate the photoreactive coumaryloxyacetyl groups into the side chain amino groups of the PLL and PLO. The resulting-coumarin-containing cationic polypeptides were spun into the PLC fibers with the anionic polysaccharide gellan in water. The mechanical strength of the coumarin-containing PIC fibers further increased upon light-irradi … More ation.3.Preparation of Biopolymer Hybrid Capsules Formed by Self-Assembly at an Aqueous Solution Interface : True spherical capsules are formed by electrostatic polysaccharide interaction between chitosan and gellan gum via polyion complex (PIC) formation in aqueous solutions. Dropwise addition of a chitosan solution into the gellan solution gave spherical capsules whose outside surface was gellan and whose inside was chitosan. The releasing properties of the capsules were examined using low molecular weight substances and high molecular weight proteins.4.Reinforced Fiber Material Inspired from the Byssogenous System of the Marine Mussel : The molecular mechanism involved in the byssogenous system of the marine mussels inspires the mew technology for creating a hybrid material in aqueous media. In a series of our studies to create the biomimetic hybrid fibers, capsules, hydrogels, and adhesives, we focused on the quinone-coupling chemistry, which occurs along with the byssus formation. The novel polysaccharide and poly(amino acid) derivatives were designed and synthesized. They have the grafted peptide side chap as the enzyme-mediated cross-linker, allowing the mechanical reinforcement of the hybrid materials. Less