New Approaches for Creating New Phosphines and Their Applications

由于有机膦作为过渡金属催化剂配体的重要性，开发高效的合成新膦化合物的方法是非常重要的。我们认识到1-炔基膦及其衍生物是合成新膦的有用的前体。碳-碳三键的化学修饰，包括亲核加成和环加成，导致了一系列新的有用的膦，否则很难合成。

Due to the importance of organophosphines as ligands for transition metal catalysts, development of efficient methods for the synthesis of new phosphines is very important. We recognized 1-alkynylphosphines and their derivatives as useful precursors for creation of new phosphines. Chemical modifications of the carbon-carbon triple bonds, including nucleophilic addition and cycloaddition, led to a wide range of new useful phosphines that are otherwise difficult to synthesize.