Tulane University Training Program for Diversity in tRanslation and Implementation research in cardioVascular disEase (DRIVE)

项目摘要/摘要：尽管在识别风险因素和使用循证医学方法方面取得了进展， 心血管（CV）疾病的管理策略，近期死亡率的下降已经停滞， 差距依然存在。总体而言，从事简历研究职业的种族和少数民族人数 低.翻译研究是一个迅速发展的领域，它将科学发现转化为 实验室、临床或人群研究转化为临床应用，而实施研究促进 将研究结果和循证干预措施纳入医疗保健政策、公共卫生和 临床环境。一支训练有素、多元化的翻译和实施科学家队伍，他们可以测试 路易斯安那州迫切需要创新的想法和先进的采用和实践证明的疗法 以及密西西比三角洲地区，那里的CV健康指标通常是全国最差的， 种族、社会经济地位和地理位置的差异有据可查。本报告的总体目标 在杜兰大学申请一个新的博士前T32培训项目是为了增加 来自代表性不足背景的翻译和实施研究人员，以建立多元化的劳动力队伍 可以解决该地区心血管健康的差异。杜兰大学多样性培训计划 心血管疾病（DRIVE）的转移和实施研究将借鉴以下方面的专业知识： 杰出的调查员为来自代表性不足背景的学员提供教学法， 他们需要的经验，技能，指导和资源，成为成功的简历翻译研究人员， 实施科学。该计划将提供深入的，结构化的培训支持，为八个博士前 来自不同背景和服务不足的候选人，利用优秀的调查人员和持续的 CV临床试验（T3）和基于社区的实施研究（T4）中的转化研究。驱动 培训计划将植根于多学科团队科学，初级和高级导师的整合， 指导学员通过他们的个性化发展计划获得关键技能和应用这些技能 在实践研究经验，以解决整个路易斯安那州和密西西比三角洲CV健康的差距 地区项目主任将由一个执行运营委员会和一个外部咨询委员会协助。 来自代表性不足背景的顾问，具有出色的研究生涯和指导经验。 导师将使用明确和经过验证的方法来促进学员的发展和成功， 所有学员都将参加一系列讲习班，讲授赠款写作、手稿写作和专业知识。 发展技能，包括优化演示、沟通和 联网拟议的培训计划旨在促进翻译的多样化， 实施劳动力，减少心血管疾病和代谢危险因素的负担，消除健康 差距，并改善路易斯安那州和全国的健康公平性。

Project Summary/Abstract: Despite advances in the identification of risk factors and use of evidence-based strategies to manage cardiovascular (CV) diseases, recent declines in mortality have stalled and race/ethnic disparities endure. Overall, the number of racial and ethnic minorities who are engaged in CV research careers is low. Translation research is a rapidly evolving field which transforms scientific discoveries arising from laboratory, clinical, or population studies into clinical applications, while implementation research promotes the integration of research findings and evidence-based interventions into healthcare policy, public health and clinical settings. A well-trained and diverse workforce of translation and implementation scientists who can test innovative ideas and advance the adoption and practice of proven therapies are sorely needed in Louisiana and the Mississippi Delta region, where CV health indicators are often poorest in the nation and health disparities by race, socioeconomic status and geography are well documented. The overall objective of this application for a new predoctoral T32 training program at Tulane University is to increase the number of translation and implementation researchers from underrepresented backgrounds to build a diverse workforce that can tackle CV health disparities in the region. The Tulane University training program for Diversity in tRanslation and Implementation research in cardioVascular disEase (DRIVE) will draw on the expertise of outstanding investigators to provide trainees from underrepresented backgrounds with the didactics, experience, skills, mentoring and resources they need to become successful researchers in CV translation and implementation sciences. The program will provide in-depth, structured training support for eight predoctoral candidates from diverse and underserved backgrounds, leveraging outstanding investigators and on-going translational research in CV clinical trials (T3) and community-based implementation studies (T4). The DRIVE training program will be rooted in multidisciplinary team science with integration of junior and senior mentors to guide the trainee via their Individualized Development Plan in acquiring critical skills and applying these skills in hands-on research experiences to address CV health disparities across Louisiana and the Mississippi Delta region. The program director will be assisted by an executive operating committee and a committee of external advisors from underrepresented backgrounds with exceptional research careers and experience in mentoring. Mentors will use defined and proven methods to enhance the development and success of the trainees, while all trainees will participate in a series of workshops that teach grant writing, manuscript writing and professional development skills, including best practice strategies to optimize presentations, communications and networking. The proposed training program seeks to contribute to diversifying the translation and implementation workforce, reducing the burden of CV diseases and metabolic risk factors, eliminating health disparities, and improving health equity in Louisiana and the nation.