课题基金 / 基金详情

REGULATION OF THE ANTIBODY RESPONSE TO MICROBIAL POLYSACCHARIDE ANTIGENS

REGULATION OF THE ANTIBODY RESPONSE TO MICROBIAL POLYSACCHARIDE ANTIGENS
微生物多糖抗原抗体反应的调节
批准号：
4688364
负责人：
P J BAKER
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4688364
关键词：
Escherichia coli Streptococcus pneumoniae T lymphocyte antibody formation antibody specificity autoantibody bacterial antigens bacterial polysaccharides genetic regulation hybridomas immune tolerance /unresponsiveness immunogenetics immunoglobulin genes immunologic memory immunoregulation immunosuppressive leukocyte activation /transformation lipopolysaccharides microorganism immunology suppressor T lymphocyte

项目摘要

项目成果

P J BAKER的其他基金

相似基金

相关文献

中文摘要
翻译
甘露聚糖可以刺激或抑制抗体 对III型肺炎球菌多糖（SSS-III）和绵羊的反应 红细胞（SRBC）;产生的效果取决于浓度， 分子大小、化学组成等制备甘露聚糖 采用 这些免疫调节作用似乎是T细胞依赖性的， 它们在无胸腺裸鼠中不能证明，并且所用的甘露聚糖不能 诱导B淋巴细胞的非特异性增殖。
英文摘要
Mannans can produce either stimulation or suppression of the antibody response to Type III pneumococcal polysaccharide (SSS-III) and sheep erythrocytes (SRBC); the effect produced depends upon the concentration, molecular size, and chemical composition of the preparation of mannan used. These immuno modulatory effects appear to be T cell dependent since they are not demonstrable in athymic nude mice and the mannans used do not induce the non-specific proliferation of B lymphocytes.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
REGULATION OF THE ANTIBODY RESPONSE TO MICROBIAL POLYSACCHARIDE ANTIGENS
GENETIC CONTROL OF THE ANTIBODY RESPONSE TO MICROBIAL ANTIGENS
海外基金