WV-INBRE:APPALACHIAN CARDIOVASCULAR RESEARCH NETWORK (ACORN)

描述（由申请人提供）：西弗吉尼亚州已被指定为一个国家，有一个历史上较低的成功率获得补助金从美国国立卫生研究院。马歇尔大学（MU）与西弗吉尼亚大学（VVVU）合作，被授予生物医学研究基础设施网络（BRIN）奖，以开始建立合作努力，赞助西弗吉尼亚大学本科院校的研究。目前的WV-INBRE（IDEA生物医学研究卓越网络）应用程序将建立在WV-BRIN奖成功的基础上。为此，MU与WVU合作，将作为由八个本科院校组成的研究网络的牵头机构。该网络的多学科研究主题将是细胞和分子生物学，重点是心血管疾病。四个本科院校的六个研究项目已被确定为完整的网络研究机构（NRI），一个机构已被指定为过渡NRI，三个institutions已被指定为网络外展机构（NOIs）。总的来说，这些学校构成了西弗吉尼亚大学研究网络的核心。行政，生物信息学和外联核心已经建立，以促进研究进展，指导和培训，以及科学家和学生在国家研究所和国家研究所的职业发展。在WVBRIN期间成功开发的阿巴拉契亚心血管研究网络（ACoRN）将扩大范围。计划建议为本科生提供研究机会，这将有助于为这些学生提供健康相关研究职业的管道。将开展与NOI外联的重要活动，以增强其成为NRI的潜力。此外，通过提供大量的研讨会，研讨会从州内和州外的科学家，研究培训和指导，并获得国家的最先进的核心设施，WV-INBRE将有助于提高WV劳动力的科学和技术知识基础。

DESCRIPTION (provided by applicant): West Virginia has been designated as a State that has a historically low success rate in obtaining grant awards from the National Institutes of Health. Marshall University (MU), in partnership with West Virginia University (VVVU), was awarded a Biomedical Research Infrastructure Network (BRIN) award to begin to build a collaborative effort to sponsor research at WV undergraduate institutions. The current WV-INBRE (IDEA Networks of Biomedical Research Excellence) application will build on the foundation of the successes of the WV-BRIN award. To this end, MU, in partnership with WVU, will serve as lead institutions to a research network consisting of eight undergraduate institutions. The multi-disciplinary research theme for this network will be cellular and molecular biology with an emphasis on cardiovascular disease. Four undergraduate institutions with six research projects have been identified as full Network Research Institutions (NRI), one institution has been designated a transitional NRI, and three insitutions have been desginated Network Outreach Institutions (NOIs). Collectively, these schools comprise the heart of the WV research network. Administrative, Bioinformatics and Outreach Cores have been established to facilitate the research progress, mentoring and training, and career development of scientists and students at the NRIs and NOIs. The successful Appalachian Cardiovascular Research Network (ACoRN) developed during WVBRIN will be expanded in scope. Programs are proposed to provide research opportunities for undergraduates students that will help serve as a pipeline for these students into health related research careers. Significant activity in outreach to NOIs will be made to enhance their potential to becoma a NRI. In addition, through providing numerous workshops, seminars from in-state and out-of-state scientists, research training and mentoring, and access to state-of-the-art core facilities, WV-INBRE will help enhance the science and technology knowledge base of the WV workforce.