Research Training in Hematology

描述(由申请人提供)： 目前的培训计划汇集了9名教职员工中的17名 各院系将重点关注对人类疾病具有广泛重要性的两个领域：血管生物学和干细胞生物学/血液恶性肿瘤。这笔赠款的主要目标是培养一批具有杰出潜力的医学博士和博士科学家，以在这些领域开发持续的、独立的研究计划。需要两个博士前职位，以利用威斯康星大学优秀的医学博士候选人和强大的研究生课程的长期传统。来自三个临床科室(内科、儿科和病理学)的临床研究员或住院医生和来自基础科学系(解剖学、生物化学、生物分子化学、病理学和药理学)的博士生将被选为四个博士后职位。该学院在基础和临床科学方面拥有广泛的专业知识，包括基因阵列和基因组学、转录和转录后基因表达、蛋白质结构分析、细胞生物学、造血和内皮细胞培养、生物医学工程、小鼠和灵长类动物模型、胚胎干细胞和骨髓移植的实验方法。该培训计划利用威斯康星大学的临床研究人员准备计划(K30赠款)，为从事转化性研究项目的候选人提供临床试验和生物统计学方面的教学培训。该项目在留住学术医学实习生方面有着良好的记录。大量合格的候选人、优秀的核心设施、机构支持和广泛的科学专业知识促进了多学科方法的发展，这将确保我们的受训人员在科学领域取得成功。

DESCRIPTION (provided by applicant): The current training program brings together seventeen faculty members from a total of nine Departments on campus to focus on two areas of broad importance for human disease: vascular biology and stem cell biology/hematologic malignancy. The primary goal of this grant is to train a mixture of M.D. and Ph.D. scientists with outstanding potential to develop a sustained, independent research program in these fields. Two predoctoral positions are requested to take advantage of the outstanding pool of M.D. Ph.D. candidates and the long tradition of strong graduate programs at the University of Wisconsin. Fellows or residents in the Clinical Investigator track from the three participating clinical Departments (Medicine, Pediatrics, and Pathology) and Ph.D. trainees from the participating basic science departments (Anatomy, Biochemistry, Biomolecular Chemistry, Pathology and Pharmacology) will be selected for the four postdoctoral positions. The faculty have broad expertise in both basic and clinical sciences, including experimental approaches in gene arrays and genomics, transcriptional and post-transcriptional gene expression, protein structural analysis, cell biology, hematopoetic and endothelial cell culture, biomedical engineering, murine and primate animal models, embryonic stems cells, and bone marrow transplantation. The training program takes advantage of the Clinical Investigator Preparatory Program (K30 grant) at the University of Wisconsin to provide didactic training in clinical trials and biostatistics for candidates pursuing translational research projects. The program has an excellent record of retaining trainees in academic medicine. The large pool of qualified candidates, excellent core facilities, institutional support, and broad range of scientific expertise fosters multidisciplinary approaches that will ensure successful careers in science for our trainees.