VALIDATION OF A REMOTE ALCOHOL SENSING DEVICE WITH ALCOHOL MEASUREMENT

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项试验是测试远程酒精传感系统的一系列研究的第一阶段。来自原型连续酒精监测装置的数据将与摄入的酒精、呼吸和血液样本的标准测量相关联。受试者将逐渐接受酒精给药至0.1 g%的水平，通过试验期间进行的呼吸测试确定。将在酒精给药程序期间和之后的指定时间点记录通过呼吸、血液和间质液测量的酒精水平。随后将对这些测量结果进行比较，以确定传感器在血液酒精浓度范围内的有效性以及snesor在研究参与者中的可靠性。进一步的协议将在越来越自然的场所测试传感器。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This trial is the first stage of a series of studies testing a remote alcohol sensing system. Data from the protoype continuous alcohol monitoring device will be correlated with standard measures of ingested alcohol, breath and blood samples. Participants will be gradually dosed with alcohol to a level of 0.1 g%, as determined by breath tests conducted during the trial. Alcohol levels as measures by breath, blood, and interstitial fluid will be documented at designated time points during and after the alcohol dosing procedure. These measures will subsequently be compared to determine the validity of the sensor over the range of blood alcohol concentrations and the reliability of the snesor across study participants. Further protocols will test the sensor in increasingly naturalistic venues.