Interdisciplinary and Translational Research Training in NeuroAIDS

描述（由申请人提供）：本申请为神经艾滋病及相关研究领域的博士生提供了一个跨学科和转化研究培训计划（ITRTP）。这是天普大学（Temple University）和德雷塞尔大学（Drexel University）两所院校的联合项目，位于宾夕法尼亚州费城附近。该计划还将整合长期倾向于医学博士/博士的培训活动和研究资源。以及宾夕法尼亚大学神经学系的艾滋病和神经病毒学临床研究培训项目。拟议的计划将通过共享资源、联合研究系列研讨会、期刊俱乐部、专题讨论会、邀请演讲者、论文指导和两所机构的教育机会，在全市范围内建立一个神经艾滋病跨学科和转化研究培训计划。这两所大学的研究生课程旨在为生物医学科学提供广泛的科学基础，包括神经科学、免疫学、微生物学、药理学和生理学。本课程包括科学传播、科学诚信与生命伦理学、统计学，以及分子与细胞神经生物学和神经生物学疾病的发病机制课程，为研究生进行神经艾滋病的论文研究做准备。在天普大学医学院，神经科学系、微生物学和免疫学系、药理学系和生理学系提供神经艾滋病和相关领域的研究机会。在工程学院有更多的研究机会。德雷塞尔大学医学院微生物与免疫学系、神经生物学与解剖学系、药理学与生理学系、生物化学与分子生物学系提供神经艾滋病及相关领域的研究机会。在生物医学工程和健康科学系统学院有更多的研究机会。该项目将两个机构的多个生物医学基础科学系与生物医学工程系结合在一起，并与附近的宾夕法尼亚大学整合了联合培训活动。随着临床艾滋病研究人员的加入，该计划不仅是跨学科的，而且使学生接触到艾滋病和神经艾滋病相关临床观点的神经艾滋病基础科学培训。坦普尔大学和德雷塞尔大学的研究人员已经建立了强大的、富有成效的、资金充足的神经艾滋病研究项目，这些项目现在已经足够支持神经艾滋病在分子研究、体外系统以及人类和非人类发病机制研究等领域的正式综合培训。

DESCRIPTION (provided by applicant): This application provides a plan for an Interdisciplinary and Translational Research Training Program (ITRTP) for predoctoral students in NeuroAIDS and related areas of research. This is a joint program from two institutions, Temple University and Drexel University, located in close proximity in Philadelphia, 'Pennsylvania. This program will also integrate training activities and research resources available in a long- tending M.D./Ph.D. and clinical research training programs in AIDS and Neurovirology based in the Department of Neurology, University of Pennsylvania. The proposed plan will create a city-wide interdisciplinary and translational research training program in NeuroAIDS through shared resources, joint research seminar series, journal club, symposia, invited speakers, thesis mentoring and educational opportunities at both institutions. The graduate curriculum at both institutions is designed to provide a broad based scientific foundation in biomedical science including Neuroscience, Immunology, Microbiology, Pharmacology and Physiology. This curriculum including Scientific Communication, Scientific Integrity and Bioethics, and Statistics, as well as courses in Molecular and Cellular Neurobiology and Pathogenesis of Neurobiological Diseases will prepare graduate student for thesis research in NeuroAIDS. Within Temple University School of Medicine, research opportunities in NeuroAIDS and related areas are available within the Department of Neuroscience, Department of Microbiology and Immunology, Department of Pharmacology, and Department of Physiology. Additional research opportunity is available in the School of Engineering. At Drexel University College of Medicine, research opportunities in NeuroAIDS and related areas are available in the Department of Microbiology and Immunology, Department of Neurobiology and Anatomy, Department of Pharmacology and Physiology and Department of Biochemistry and Molecular Biology. Additional research opportunities are available in the School of Biomedical Engineering and Health Science Systems. This program brings together multiple biomedical basic science departments with biomedical engineering at two institutions, and integrates joint training activities with nearby University of Pennsylvania. With the inclusion of clinical AIDS investigators, the proposed program is not only interdisciplinary, but exposes students to training in neuroAIDS basic sciences to AIDS and NeuroAIDS related clinical perspectives. Investigators at Temple and Drexel have built strong, productive and well-funded NeuroAIDS research programs that are now sufficiently established to support formal comprehensive training in NeuroAIDS in areas ranging from molecular studies, in vitro systems, and pathogenesis studies in human and non-human.